Evidence map›Paper›PMID 27565833›Full record

ArticleNitric oxide : biology and chemistry2016

A mathematical model for the role of N

Yien Liu, Donald G Buerk, Kenneth A Barbee, Dov Jaron

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nitric oxide : biology and chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. The chemical biology of dinitrogen trioxide.Redox biochemistry and chemistry · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yien LiuSchool of Biomedical Engineering, Science and Health Systems, Drexel University, 3140 Market St., Philadelphia, PA 19104, USA.
Donald G BuerkSchool of Biomedical Engineering, Science and Health Systems, Drexel University, 3140 Market St., Philadelphia, PA 19104, USA.
Kenneth A BarbeeSchool of Biomedical Engineering, Science and Health Systems, Drexel University, 3140 Market St., Philadelphia, PA 19104, USA.
Dov JaronSchool of Biomedical Engineering, Science and Health Systems, Drexel University, 3140 Market St., Philadelphia, PA 19104, USA. Electronic address: dov.jaron@drexel.edu.
Drexel University · US

Funding

Multiscale, Transport-Dependent NO Signaling: Cells to Vascular NetworksU01HL116256 · NHLBI · DREXEL UNIVERSITY · PI JARON, DOV · 2013 to 2017
$3.4M
NHLBI NIH HHS U01 HL116256
6 · The paper itself

Abstract

Nitrite infusion into the bloodstream has been shown to elicit vasodilation and protect against ischemia-reperfusion injury through nitric oxide (NO) release in hypoxic conditions. However, the mechanism by which nitrite-derived NO escapes scavenging by hemoglobin in the erythrocyte has not been fully elucidated, owing in part to the difficulty in measuring the reactions and transport on NO in vivo. We developed a mathematical model for an arteriole and surrounding tissue to examine the hypothesis that dinitrogen trioxide (N

Indexed as

AnimalsArteriolesBiological AvailabilityBlood Flow VelocityHypoxiaModels, BiologicalNitric OxideNitritesNitrogen OxidesOxygenVasodilationNitric OxideNitritesNitrogen Oxidesnitrogen trioxideOxygenArterioleDinitrogen trioxideHypoxic vasodilationNitrite infusionNitrous anhydride

Identifiers

PMID27565833
PMCPMC5343674
OpenAlexW2509691512

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.