ArticleBMC genomics2016
Small RNA and degradome profiling reveals miRNA regulation in the seed germination of ancient eudicot Nelumbo nucifera.
Article in BMC genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- Lotus Seeds: Current Molecular Biology Insights and Future Perspectives as a Prominent Biological Resource.Plants (Basel, Switzerland) · 2026Review
- Comprehensive Profiling of the miRNome and Degradome Reveals Regulatory Signatures of Seed Aging and Germination.International journal of molecular sciences · 2025Article
- Improved Degradome Sequencing Protocol via Reagent Recycling from sRNAseq Library Preparations.International journal of molecular sciences · 2025Article
- Comparative miRNAome combined with transcriptome and degradome analysis reveals a novel miRNA-mRNA regulatory network associated with starch metabolism affecting pre-harvest sprouting resistance in wheat.BMC plant biology · 2025Article
- Differentially Expressed Conserved Plant Vegetative Phase-Change-Related microRNAs in Mature and Rejuvenated Silver Birch In Vitro Propagated Tissues.Plants (Basel, Switzerland) · 2023Article
- Rapid sequence and functional diversification of a miRNA superfamily targeting calcium signaling components in seed plants.The New phytologist · 2022Article
- Global DNA Methylation and mRNA-miRNA Variations Activated by Heat Shock Boost Early Microspore Embryogenesis in Cabbage (International journal of molecular sciences · 2022Article
- Whole-Transcriptome Analysis Reveals Autophagy Is Involved in Early Senescence ofFrontiers in plant science · 2022Article
- Salt and Drought Stress Responses in Cultivated Beets (Plants (Basel, Switzerland) · 2021Review
- Deep Sequencing of Small RNA Reveals the Molecular Regulatory Network ofInternational journal of molecular sciences · 2021Article
- Barley Seeds miRNome Stability during Long-Term Storage and Aging.International journal of molecular sciences · 2021Article
- The role of RNA-binding protein, microRNA and alternative splicing in seed germination: a field need to be discovered.BMC plant biology · 2021Review
- Whole-Transcriptome RNA Sequencing Reveals the Global Molecular Responses and CeRNA Regulatory Network of mRNAs, lncRNAs, miRNAs and circRNAs in Response to Salt Stress in Sugar Beet (International journal of molecular sciences · 2020Article
- The Latest Studies on Lotus (International journal of molecular sciences · 2019Review
- Unravelling miRNA regulation in yield of rice (Oryza sativa) based on differential network model.Scientific reports · 2018Article
- Expression dynamics of miRNAs and their targets in seed germination conditions reveals miRNA-ta-siRNA crosstalk as regulator of seed germination.Scientific reports · 2018Article
- Integrated mRNA and microRNA transcriptome analysis reveals miRNA regulation in response to PVA in potato.Scientific reports · 2017Article
- Identification of Submergence-Responsive MicroRNAs and Their Targets Reveals Complex MiRNA-Mediated Regulatory Networks in Lotus (Frontiers in plant science · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicroRNAs (miRNAs) play important roles in plant growth and development. MiRNAs and their targets have been widely studied in model plants, but limited knowledge is available concerning this small RNA population and their targets in sacred lotus (Nelumbo nucifera Gaertn.).
resultsIn this study, a total of 145 known miRNAs belonging to 47 families and 78 novel miRNAs were identified during seed germination using high-throughput small RNA sequencing. Furthermore, some miRNA families which have not yet been reported in monocot or eudicot species were detected in N. nucifera, indicating that these miRNAs was divergence from monocots and core eudicots during evolution. Using degradome sequencing, 2580 targets were detected for all the miRNAs. GO (Gene Ontology) and KEGG pathway analyses showed that many target genes enriched in "regulation of transcription" and involved in "carbohydrate", "amino acid and energy metabolism". Nine miRNAs and three corresponding targets of them were further validated by quantitative RT-PCR.
conclusionsThe results present here suggested that many miRNAs were involved in the regulation of seed germination of sacred lotus, providing a foundation for future studies of sacred lotus seed longevity. Comparative analysis of miRNAs from different plants also provided insight into the evolutionary gains and losses of miRNAs in plants.
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