Evidence map›Paper›PMID 27565279›Full record

ArticleValue in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

A PROMIS Measure of Neuropathic Pain Quality.

Robert L Askew, Karon F Cook, Francis J Keefe, Cindy J Nowinski, David Cella, Dennis A Revicki, Esi M Morgan DeWitt, Kaleb Michaud, Dace L Trence, Dagmar Amtmann

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04742790 (Clinical Calibration and Evaluation of the QSPainRelief Platform in Patients With Disabling Pain Using Functional Biomarkers of Nociception, Sedation and Cognition), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04742790 naunknown statusnot on this map

Clinical Calibration and Evaluation of the QSPainRelief Platform in Patients With Disabling Pain Using Functional Biomarkers of Nociception, Sedation and Cognition

TypeinterventionalSponsorUniversité Catholique de LouvainRan2021 to 2024Enrolled180ConditionsPost-operative PainArmsScalp electroencephalography (EEG), Laser-evoked potentials (LEPs), Cognitive auditory-evoked potentials (P300), Cervical somatosensory-evoked potentials, Pupillometry
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Neuropathic pain in burn patients - A common problem with little literature: A systematic review.Burns : journal of the International Society for Burn Injuries · 2024
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Regenerative Peripheral Nerve Interface Surgery to Treat Chronic Postamputation Pain: A Prospective Study in Major Lower Limb Amputation Patients.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Surgical treatment of painful neuroma in amputated and non-amputated patients: does the level of neurotomy affect clinical outcomes?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  11. Relationship of cancer-related fatigue with psychoneurophysiological (PNP) symptoms in breast cancer survivors.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2024
    Article
  12. Article
  13. Article
  14. Observational
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  16. Measuring PROMIS pain interference in German patients with chronic conditions: calibration, validation, and cross-cultural use of item parameters.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Robert L AskewPsychology Department, Stetson University, DeLand, FL, USA. Electronic address: raskew@stetson.edu.
Karon F CookFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Francis J KeefeDuke University, Durham, NC, USA.
Cindy J NowinskiFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
David CellaFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Dennis A RevickiEvidera, Bethesda, MD, USA.
Esi M Morgan DeWittCincinnati Children's Hospital, Cincinnati, OH, USA.
Kaleb MichaudUniversity of Nebraska Medical Center, Omaha, NE, USA; National Data Bank for Rheumatic Diseases, Wichita, KS, USA.
Dace L TrenceUniversity of Washington, Seattle, WA, USA.
Dagmar AmtmannUniversity of Washington, Seattle, WA, USA.
Northwestern University · USUniversity of Washington · USCincinnati Children's Hospital Medical Center · USDuke University · USIthaka Harbors · USStetson University · USThe National Databank for Rheumatic Diseases · US

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9M
The National Person-Centered Assessment Resource (PCAR)U2CCA186878 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GERSHON, RICHARD · 2014 to 2018
$11.9M
NIH PROMIS Statistical Coordinating Center(RMI)U01AR052177 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CELLA, DAVID · 2004 to 2010
$10.6M
NCI NIH HHS P30 CA060553NCI NIH HHS U2C CA186878NIAMS NIH HHS U01 AR052177
6 · The paper itself

Abstract

objectivesNeuropathic pain (NP) is a consequence of many chronic conditions. This study aimed to develop an unidimensional NP scale with scores that represent levels of NP and distinguish between individuals with NP and non-NP conditions.

methodsA candidate item pool of 42 pain quality descriptors was administered to participants with osteoarthritis, rheumatoid arthritis, diabetic neuropathy, and cancer chemotherapy-induced peripheral neuropathy. A subset of pain quality descriptors (items) that best distinguished between participants with and those without NP conditions were identified. Dimensionality of pain descriptors was evaluated in a development sample and cross-validated in a holdout sample. Item responses were calibrated using an item response theory model, and scores were generated on a T-score metric. NP scale scores were evaluated in terms of the reliability, validity, and ability to distinguish between participants with and without conditions typically associated with NP.

resultsOf the 42 initial items, 5 were identified for the Patient-Reported Outcome Measurement Information System (PROMIS) Neuropathic Pain Quality Scale. T scores exhibited good discriminatory ability on the basis of receiver-operator characteristic analysis. Score thresholds that optimize sensitivity and specificity were identified. Construct, criterion, and discriminant validity, and reliability of scale scores were supported.

conclusionsThe five-item Patient-Reported Outcome Measurement Information System (PROMIS PQ-Neuro) Neuropathic Pain Quality Scale is a short and practical measure that can be used to identify patients more likely to have NP and to distinguish levels of NP. The data collected will support future research that targets other unidimensional pain quality domains (e.g., nociceptive pain).

Indexed as

NeuralgiaAdultAgedFemaleHumansMaleMiddle AgedPain MeasurementQuality of LifeSelf ReportTreatment Outcomemeasurementneuropathypainpatient-reported outcomesPROMIS

Identifiers

PMID27565279
PMCPMC5002873
OpenAlexW2315292509

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.