Evidence map›Paper›PMID 27565155›Full record

ArticleDysphagia2017

Pharyngeal Pressure and Timing During Bolus Transit.

Chelsea C Walczak, Corinne A Jones, Timothy M McCulloch

Abstract read
In one paragraph

Article in Dysphagia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A systematic review of current methodology of high resolution pharyngeal manometry with and without impedance.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Swallowing biomechanics before and following multi-level upper airway surgery for obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Pharyngeal peristaltic pressure variability, operational range, and functional reserve.American journal of physiology. Gastrointestinal and liver physiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chelsea C WalczakDivision of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, WI, USA.
Corinne A JonesDivision of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, WI, USA.
Timothy M McCullochDivision of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, WI, USA. mccull@surgery.wisc.edu.

Funding

NEUROSCIENCE TRAINING PROGRAMT32GM007507 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HALLORAN, MARY C · 1985 to 2017
$9.3M
High Resolution Manometry: A Novel Pattern Recognition Method for DysphagiaR21DC011130 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI MCCULLOCH, TIMOTHY M · 2011 to 2012
$398k
NIDCD NIH HHS R21 DC011130NIGMS NIH HHS T32 GM007507
6 · The paper itself

Abstract

Determining intrabolus pressure (IBP) at the upper esophageal sphincter (UES) and in the esophagus has given compelling evidence that IBP can be a predictor for swallowing dysfunction. Studies have looked most superiorly at the low hypopharynx region but there has been no inquiry into what IBP measures throughout the entire pharynx can tell us. We present a study to describe the pressures within and surrounding the moving bolus throughout the pharynx and into the UES. Simultaneous high-resolution manometry (HRM) and videofluoroscopy were performed in ten healthy subjects swallowing ten 10 mL thin-liquid barium boluses. Three events surrounding bolus movement were tracked via videofluoroscopy, and two additional events were found using manometric measures. As the bolus passes through the pharynx, low pressure is created at and below the head of the bolus. A modest pressure increase is seen as the bolus passes through the pharynx, and finally, high pressure is observed at the bolus tail, followed by an even larger pressure generation of a clearance event. HRM allows for greater resolution in data collection in the pharynx and in this study, aided in identifying semi-unique characteristics around the hypopharynx and the UES which are consistent with the complex anatomy of the regions and the transition of the UES from active closure to relaxed opening. In the future, additional studies designed to look at aged and diseased populations may lead to better understanding of disease etiology, and treatment options.

Indexed as

AdultDeglutitionEsophageal Sphincter, UpperFemaleFluoroscopyHealthy VolunteersHumansMaleManometryMiddle AgedPharynxPressureYoung AdultDeglutitionDeglutition disordersHigh-resolution manometryIntrabolus PressureVideofluoroscopy

Identifiers

PMID27565155
PMCPMC5832365

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.