Evidence map›Paper›PMID 27564922›Full record

ArticleNature microbiology2016

The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity.

Hong-Wei Su, Jun-Hao Zhu, Hao Li, Rong-Jun Cai, Christopher Ealand, Xun Wang, Yu-Xiang Chen, Masood Ur Rehman Kayani, Ting F Zhu, Danesh Moradigaravand and 3 more

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Nature microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 90 citations in OpenAlex.

  1. Latently and uninfected healthcare workers exposed to TB make protective antibodies againstProceedings of the National Academy of Sciences of the United States of America · 2017
    Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Interplay between mistranslation and oxidative stress inArhiv za higijenu rada i toksikologiju · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. The Biological and Clinical Aspects of a Latent Tuberculosis Infection.Tropical medicine and infectious disease · 2022
    Review
  13. Review
  14. The evolving biology ofFrontiers in cellular and infection microbiology · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Bacterial translation machinery for deliberate mistranslation of the genetic code.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Hong-Wei SuCollaboration Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, School of Medicine, Tsinghua University, Beijing 100084, China.
Jun-Hao ZhuCollaboration Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, School of Medicine, Tsinghua University, Beijing 100084, China.
Hao LiCollaboration Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, School of Medicine, Tsinghua University, Beijing 100084, China.
Rong-Jun CaiCollaboration Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, School of Medicine, Tsinghua University, Beijing 100084, China.
Christopher EalandFaculty of Health Sciences, DST/NRF Centre of Excellence for Biomedical TB Research, University of the Witwatersrand, National Health Laboratory Service, Johannesburg 2193, South Africa.
Xun WangCollaboration Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, School of Medicine, Tsinghua University, Beijing 100084, China.
Yu-Xiang ChenCollaboration Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, School of Medicine, Tsinghua University, Beijing 100084, China.
Masood Ur Rehman KayaniCenter for Synthetic and Systems Biology, MOE Key Laboratory of Bioinformatics, Collaboration Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Ting F ZhuCenter for Synthetic and Systems Biology, MOE Key Laboratory of Bioinformatics, Collaboration Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Danesh MoradigaravandWellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Hairong HuangNational Clinical Laboratory on Tuberculosis, Beijing Tuberculosis and Thoracic Tumor Institute, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Bavesh D KanaFaculty of Health Sciences, DST/NRF Centre of Excellence for Biomedical TB Research, University of the Witwatersrand, National Health Laboratory Service, Johannesburg 2193, South Africa.
Babak JavidCollaboration Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, School of Medicine, Tsinghua University, Beijing 100084, China.ORCID http://orcid.org/0000-0002-6354-6305
Tsinghua University · CNNational Health Laboratory Service · ZACapital Medical University · CNPeking University · CNWellcome Sanger Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although regulation of translation fidelity is an essential process

Indexed as

Protein BiosynthesisTransfer RNA AminoacylationAsparagineCodonDrug Resistance, BacterialEscherichia coliGlutamineMutationMycobacterium smegmatisNitrogenous Group TransferasesRifampinAsparagineCodonGlutamineNitrogenous Group TransferasesRifampin

Identifiers

PMID27564922
OpenAlexW2508609323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.