ArticlePloS one2016
Epigenome Editing of Potato by Grafting Using Transgenic Tobacco as siRNA Donor.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- Epigenetic crop improvement: Integrating ENCODE strategies into horticultural breeding.Horticulture research · 2025Article
- Gaining insights into epigenetic memories through artificial intelligence and omics science in plants.Journal of integrative plant biology · 2025Review
- Modern and historical uses of plant grafting to engineer development, stress tolerance, chimeras, and hybrids.The Plant journal : for cell and molecular biology · 2025Review
- Omics Profiles of Non-GM Tubers from Transgrafted Potato with a GM Scion.Food safety (Tokyo, Japan) · 2023Article
- Long distance signalling and epigenetic changes in crop grafting.Frontiers in plant science · 2023Review
- Harnessing epigenetic variability for crop improvement: current status and future prospects.Genes & genomics · 2022Review
- Omics Profiles of Non-transgenic Scion Grafted on Transgenic RdDM Rootstock.Food safety (Tokyo, Japan) · 2022Article
- Soma-to-germline RNA communication.Nature reviews. Genetics · 2022Review
- Will epigenetics be a key player in crop breeding?Frontiers in plant science · 2022Review
- Reinvigoration/Rejuvenation Induced through Micrografting of Tree Species: Signaling through Graft Union.Plants (Basel, Switzerland) · 2021Review
- Effect of Transgenic Rootstock Grafting on the Omics Profiles in Tomato.Food safety (Tokyo, Japan) · 2021Article
- Application of Genome Editing in Tomato Breeding: Mechanisms, Advances, and Prospects.International journal of molecular sciences · 2021Review
- Rapid analysis of GBSS1 and Vinv genes expressed in potato tubers using microtubers produced in liquid culture medium.Plant cell reports · 2020Article
- MSH1-induced heritable enhanced growth vigor through grafting is associated with the RdDM pathway in plants.Nature communications · 2020Article
- Vegetable Grafting From a Molecular Point of View: The Involvement of Epigenetics in Rootstock-Scion Interactions.Frontiers in plant science · 2020Review
- Dynamic regulation of plasmodesmatal permeability and its application to horticultural research.Horticulture research · 2019Review
- Article
- Transgene-independent heredity of RdDM-mediated transcriptional gene silencing of endogenous genes in rice.Plant biotechnology journal · 2018Article
- Exploiting induced and natural epigenetic variation for crop improvement.Nature reviews. Genetics · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, it is possible to induce heritable transcriptional gene silencing (TGS) via RNA-directed DNA methylation (RdDM) using artificially synthesized small RNA (siRNA) homologous to the 5'-flanking region of the target gene. As the siRNA signal with a specific RNA determinant moves through plasmodesmata and sieve elements, we attempted to induce TGS of a transgene and an endogenous gene of potato (Solanum tuberosum) rootstock by grafting using siRNA produced in a tobacco (Nicotiana benthamiana) scion. Our results provide evidence that this system can induce TGS of target genes in tubers formed on potato rootstock. The TGS is maintained in the progeny tubers lacking the transported siRNAs. Our findings reveal that epigenome editing using mobile RNA has the potential to allow breeding of artificial sport cultivars in vegetative propagation crops.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.