ArticleEndocrinology2016
Estrogen Stimulation of Kiss1 Expression in the Medial Amygdala Involves Estrogen Receptor-α But Not Estrogen Receptor-β.
Article in Endocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 50 citations in OpenAlex.
- Hypothalamic control of puberty: from neuronal circuits to mechanisms for its metabolic regulation.Reviews in endocrine & metabolic disorders · 2026Review
- Kisspeptin made in the preoptic area is required for normal estradiol-induced LH surges and optimal fertility in females.Endocrinology · 2026Article
- Anatomic distribution of kisspeptin neurons in the adult sheep amygdala: Associations with sex, estrogen receptor alpha, androgen receptor, and sexual partner preference.Journal of neuroendocrinology · 2025Article
- Sex difference in developmental changes in visualized Kiss1 neurons in newly generated Kiss1-Cre rats.The Journal of reproduction and development · 2023Article
- Regulatory T cells play a crucial role in maintaining sperm tolerance and male fertility.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- The molecular phenotype of kisspeptin neurons in the medial amygdala of female mice.Frontiers in endocrinology · 2023Article
- GnRH pulse generator frequency is modulated by kisspeptin and GABA-glutamate interactions in the posterodorsal medial amygdala in female mice.Journal of neuroendocrinology · 2022Article
- Anxiety and Depression: What Do We Know of Neuropeptides?Behavioral sciences (Basel, Switzerland) · 2022Review
- Developmental sex differences in the peri-pubertal pattern of hypothalamic reproductive gene expression, including Kiss1 and Tac2, may contribute to sex differences in puberty onset.Molecular and cellular endocrinology · 2022Article
- Running the Female Power Grid Across Lifespan Through Brain Estrogen Signaling.Annual review of physiology · 2022Review
- Hypothalamic Kisspeptin Neurons and the Control of Homeostasis.Endocrinology · 2022Review
- Neuroendocrine mechanisms underlying estrogen positive feedback and the LH surge.Frontiers in neuroscience · 2022Review
- Application of Transgenic Zebrafish Models for Studying the Effects of Estrogenic Endocrine Disrupting Chemicals on Embryonic Brain Development.Frontiers in pharmacology · 2022Review
- Estrogens regulate early embryonic development of the olfactory sensory system via estrogen-responsive glia.Development (Cambridge, England) · 2022Article
- Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala.Metabolites · 2021Review
- Progesterone Receptors in AVPV Kisspeptin Neurons Are Sufficient for Positive Feedback Induction of the LH Surge.Endocrinology · 2021Article
- Estrogen Regulation of the Molecular Phenotype and Active Translatome of AVPV Kisspeptin Neurons.Endocrinology · 2021Article
- Functions of galanin, spexin and kisspeptin in metabolism, mood and behaviour.Nature reviews. Endocrinology · 2021Review
- Puberty, A Sensitive Window of Hypothalamic Development and Plasticity.Endocrinology · 2021Review
- Mating-induced increase in Kiss1 mRNA expression in the anteroventral periventricular nucleus prior to an increase in LH and testosterone release in male rats.The Journal of reproduction and development · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The neuropeptide kisspeptin, encoded by Kiss1, regulates reproduction by stimulating GnRH secretion. Neurons synthesizing kisspeptin are predominantly located in the hypothalamic anteroventral periventricular (AVPV) and arcuate nuclei, but smaller kisspeptin neuronal populations also reside in extrahypothalamic brain regions, such as the medial amygdala (MeA). In adult rodents, estradiol (E
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.