ReviewInternational journal of environmental research and public health2016
Nutrition in the First 1000 Days: The Origin of Childhood Obesity.
Review in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
155 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Effectiveness of Context-Specific Social and Behaviour Change (SBC) Interventions in Improving Child Diet in Ethiopia: A Systematic Review and Meta-Analysis.Maternal & child nutrition · 2026Pooled it
- Effective dietary interventions during pregnancy: a systematic review and meta-analysis of behavior change techniques to promote healthy eating.BMC pregnancy and childbirth · 2025Pooled it
- Systematic review of associations between gut microbiome composition and stunting in under-five children.NPJ biofilms and microbiomes · 2024Pooled it
- Adoption, implementation, and sustainability of early childhood feeding, nutrition and active play interventions in real-world settings: a systematic review.The international journal of behavioral nutrition and physical activity · 2023Pooled it
- Factors Associated with Eating in the Absence of Hunger among Children and Adolescents: A Systematic Review.Nutrients · 2022Pooled it
- Identification and Evaluation of Tools Utilised for Measuring Food Provision in Childcare Centres and Primary Schools: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Confirmatory factor analysis of the infant feeding styles questionnaire in infant and toddler child care teachers.Appetite · 2023Trial
- Trial
- Leptin partially mediates the association between early-life nutritional supplementation and long-term glycemic status among women in a Guatemalan longitudinal cohort.The American journal of clinical nutrition · 2020Trial
- Zika virus infection in pregnancy and infant growth, body composition in the first three months of life: a cohort study.Scientific reports · 2019Trial
- Clinical evaluation of two different protein content formulas fed to full-term healthy infants: a randomized controlled trial.BMC pediatrics · 2018Trial
- MaternalNutrients · 2026Review
- Validation and cultural adaptation of the pregnancy-adapted Mediterranean Diet Adherence Screener (ITpreg-MEDAS) in Italian pregnant women.European journal of nutrition · 2026Article
- Small intestine microbiota development prevents early-life adiposity via IL-22-mediated intestinal PPARα suppression.bioRxiv : the preprint server for biology · 2026Article
- BMI-for-age Z-score trajectories in early childhood: a comparison of GMM and KML and associated antenatal and postnatal factors.World journal of pediatrics : WJP · 2026Article
- Poor Water Quality and Food Insecurity in Ecuador: Disparities in Exposure and Associations With Young Child Feeding Practices.Journal of the Academy of Nutrition and Dietetics · 2026Article
- Nurturing Bonds: A Qualitative Exploration of Breastfeeding and Responsive Feeding Practices in Samoan Mother-Infants Dyads.American journal of human biology : the official journal of the Human Biology Council · 2026Article
- Sociodemographic, pregnancy-related and lifestyle determinants of adherence to Italian dietary guidelines during pregnancy: a cross-sectional study in a representative sample of Italian pregnant women.European journal of nutrition · 2026Article
- Characterization of food portion size in children from 6 months to 8 years of age: a descriptive analysis.European journal of nutrition · 2026Article
- Predicting rapid weight gain in six-month-old infants: an exploratory modeling study.Pediatric research · 2026Article
95 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood obesity is a major global issue. Its incidence is constantly increasing, thereby offering a threatening public health perspective. The risk of developing the numerous chronic diseases associated with this condition from very early in life is significant. Although complex and multi-factorial, the pathophysiology of obesity recognizes essential roles of nutritional and metabolic aspects. Particularly, several risk factors identified as possible determinants of later-life obesity act within the first 1000 days of life (i.e., from conception to age 2 years). The purpose of this manuscript is to review those key mechanisms for which a role in predisposing children to obesity is supported by the most recent literature. Throughout the development of the human feeding environment, three different stages have been identified: (1) the prenatal period; (2) breast vs. formula feeding; and (3) complementary diet. A deep understanding of the specific nutritional challenges presented within each phase might foster the development of future preventive strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.