Evidence map›Paper›PMID 27563858›Full record

ReviewMolecules (Basel, Switzerland)2016

Plant Cell Cancer: May Natural Phenolic Compounds Prevent Onset and Development of Plant Cell Malignancy? A Literature Review.

Hassan Rasouli, Mohammad Hosein Farzaei, Kamran Mansouri, Sara Mohammadzadeh, Reza Khodarahmi

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
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  3. Review
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  6. Article
  7. Review
  8. Article
  9. Nano-Nutraceuticals for Health: Principles and Applications.Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia · 2023
    Review
  10. Article
  11. Article
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  15. Removal of Cr(vi) andRSC advances · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hassan RasouliMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah 6714967346, Iran. h3n.rasouli@gmail.com.
Mohammad Hosein FarzaeiMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah 6714967346, Iran. mh.farzaei@gmail.com.
Kamran MansouriMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah 6714967346, Iran. kamranmansouri@gmail.com.
Sara MohammadzadehMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah 6714967346, Iran. sara3ms@yahoo.com.
Reza KhodarahmiMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah 6714967346, Iran. rkhodarahmi@mbrc.ac.ir.
Kermanshah University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenolic compounds (PCs) are known as a chemically diverse category of secondary and reactive metabolites which are produced in plants via the shikimate-phenylpropanoid pathways. These compounds-ubiquitous in plants-are an essential part of the human diet, and are of considerable interest due to their antioxidant properties. Phenolic compounds are essential for plant functions, because they are involved in oxidative stress reactions, defensive systems, growth, and development. A large body of cellular and animal evidence carried out in recent decades has confirmed the anticancer role of PCs. Phytohormones-especially auxins and cytokinins-are key contributors to uncontrolled growth and tumor formation. Phenolic compounds can prevent plant growth by the endogenous regulation of auxin transport and enzymatic performance, resulting in the prevention of tumorigenesis. To conclude, polyphenols can reduce plant over-growth rate and the development of tumors in plant cells by regulating phytohormones. Future mechanistic studies are necessary to reveal intracellular transcription and transduction agents associated with the preventive role of phenolics versus plant pathological malignancy cascades.

Indexed as

Plant TumorsAntioxidantsCytokininsHumansIndoleacetic AcidsPhenolsPlant Growth RegulatorsAntioxidantsCytokininsIndoleacetic AcidsPhenolsPlant Growth Regulatorscancerflavonoidsphenolic compoundssecondary metabolites

Identifiers

PMID27563858
PMCPMC6274315
OpenAlexW2516417294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.