Evidence map›Paper›PMID 27563705›Full record

ReviewCellular and molecular life sciences : CMLS2017

Interplay of mitochondrial metabolism and microRNAs.

Julian Geiger, Louise T Dalgaard

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. miRNAs in Heart Development and Disease.International journal of molecular sciences · 2024
    Review
  19. Article
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Julian GeigerDepartment of Science and Environment, Roskilde University, Universitetsvej 1, Bldg. 28A1, 4000, Roskilde, Denmark.ORCID 0000-0001-8434-1459
Louise T DalgaardDepartment of Science and Environment, Roskilde University, Universitetsvej 1, Bldg. 28A1, 4000, Roskilde, Denmark. ltd@ruc.dk.ORCID 0000-0002-3598-2775

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria are important organelles in cellular metabolism. Several crucial metabolic pathways such as the energy producing electron transport chain or the tricarboxylic acid cycle are hosted inside the mitochondria. The proper function of mitochondria depends on the import of proteins, which are encoded in the nucleus and synthesized in the cytosol. Micro-ribonucleic acids (miRNAs) are short non-coding ribonucleic acid (RNA) molecules with the ability to prevent messenger RNA (mRNA)-translation or to induce the degradation of mRNA-transcripts. Although miRNAs are mainly located in the cytosol or the nucleus, a subset of ~150 different miRNAs, called mitomiRs, has also been found localized to mitochondrial fractions of cells and tissues together with the subunits of the RNA-induced silencing complex (RISC); the protein complex through which miRNAs normally act to prevent translation of their mRNA-targets. The focus of this review is on miRNAs and mitomiRs with influence on mitochondrial metabolism and their possible pathophysiological impact.

Indexed as

Amino AcidsAnimalsCitric Acid CycleHumansLipid MetabolismMicroRNAsMitochondriaMitochondrial DynamicsNonsense Mediated mRNA DecayProtein BiosynthesisRNA-Induced Silencing ComplexRNA, MessengerRNA TransportAmino AcidsMicroRNAsRNA-Induced Silencing ComplexRNA, MessengerMetabolismmiRNAMitochondriamitomiR

Identifiers

PMID27563705
PMCPMC11107739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.