Evidence map›Paper›PMID 27563670›Full record

Trial reportBioMed research international2016

Effects of 8-Week Hatha Yoga Training on Metabolic and Inflammatory Markers in Healthy, Female Chinese Subjects: A Randomized Clinical Trial.

Neng Chen, Xianghou Xia, Liqiang Qin, Li Luo, Shufen Han, Guiping Wang, Ru Zhang, Zhongxiao Wan

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 5 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Significance of Yoga for the Management of Dyslipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2025
    Review
  8. What Do We Know About Prevention of Frailty in Women?American journal of lifestyle medicine · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Yoga, immunity and COVID-19: A scoping review.Journal of family medicine and primary care · 2022
    Article
  15. Review
  16. Article
  17. Yoga effectively reduces fatigue and symptoms of depression in patients with different types of cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Neng ChenDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, 199 Renai Road, Suzhou 215123, China.
Xianghou XiaDepartment of Breast Surgery, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022, China.
Liqiang QinDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, 199 Renai Road, Suzhou 215123, China.ORCID 0000-0002-5231-2562
Li LuoSchool of Physical Education and Sports Science, Soochow University, Suzhou 215006, China.ORCID 0000-0002-0536-0481
Shufen HanDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, 199 Renai Road, Suzhou 215123, China.
Guiping WangLaboratory Animal Center, Soochow University, 199 Renai Road, Suzhou 215123, China.
Ru ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, 199 Renai Road, Suzhou 215123, China.
Zhongxiao WanDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, 199 Renai Road, Suzhou 215123, China; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Disease, Soochow University, 199 Renai Road, Suzhou 215123, China.ORCID 0000-0002-6297-5933
Soochow University · CNZhejiang Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to determine the effects of an 8 wk Hatha yoga training on blood glucose, insulin, lipid profiles, endothelial microparticles (EMPs), and inflammatory status in healthy, lean, and female Chinese subjects. A total of 30 healthy, female Chinese subjects were recruited and randomized into control or yoga practice group. The yoga practice included 8 wks of yoga practice (2 times/wk) for a total of 16 times. Fasting blood samples were collected before and after yoga training. Plasma was isolated for the measurement of lipid profiles, glucose, insulin, EMPs, and inflammatory cytokines. Whole blood was cultured ex vivo and stimulated with lipopolysaccharide (LPS) and Pam3Cys-SK4. Peripheral blood mononuclear cells (PBMCs) were isolated for the measurement of TLR2 and TLR4 protein expression. Yoga practice significantly reduced plasma cholesterol, LDL-cholesterol, insulin levels, and CD31+/CD42b- EMPs. Cultured whole blood from the yoga group has reduced proinflammatory cytokines secretion both at unstimulated condition and when stimulated with Pam3Cys-SK4; this might be associated with reduced TLR2 protein expression in PBMCs after yoga training. Hatha yoga practice in healthy Chinese female subjects could improve hallmarks related to MetS; thus it can be considered as an ancillary intervention in the primary MetS prevention for the healthy population. This trial is registered with ChiCTR-IOR-14005747.

Indexed as

YogaAdolescentAdultCholesterol, LDLCytokinesFemaleHumansInflammation MediatorsInsulinLeukocytes, MononuclearToll-Like Receptor 2Toll-Like Receptor 4Cholesterol, LDLCytokinesInflammation MediatorsInsulinTLR2 protein, humanTLR4 protein, humanToll-Like Receptor 2Toll-Like Receptor 4

Identifiers

PMID27563670
PMCPMC4987461
OpenAlexW2493737542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.