ArticleSpringerPlus2016
Japanese traditional dietary fungus koji Aspergillus oryzae functions as a prebiotic for Blautia coccoides through glycosylceramide: Japanese dietary fungus koji is a new prebiotic.
Article in SpringerPlus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 62 citations in OpenAlex.
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- The gut microbiota genus Blautia is associated with skeletal muscle mass reduction in community-dwelling older Japanese adults: the Wakayama Study.European geriatric medicine · 2025Article
- Intestinal Microbiota Is a Key Target for Load Swimming to Improve Anxiety Behavior and Muscle Strength in Shank 3Molecular neurobiology · 2024Article
- Blautia coccoides and its metabolic products enhance the efficacy of bladder cancer immunotherapy by promoting CD8Journal of translational medicine · 2024Article
- A Decrease in the Hardness of Feces with Added Glucosylceramide Extracted from KojiLife (Basel, Switzerland) · 2024Article
- Intestinal microbiome and maternal mental health: preventing parental stress and enhancing resilience in mothers.Communications biology · 2024Article
- Dysbiosis of Gut Microbiota in Patients with Chronic Kidney Disease.Internal medicine (Tokyo, Japan) · 2024Article
- Integrating microbial 16S rRNA sequencing and non-targeted metabolomics to reveal sexual dimorphism of the chicken cecal microbiome and serum metabolome.Frontiers in microbiology · 2024Article
- Gut microbiome and metabolome library construction based on age group using short-read and long-read sequencing techniques in Korean traditional canine species Sapsaree.Frontiers in microbiology · 2024Article
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- The postbiotic potential ofFrontiers in microbiology · 2024Review
- Mouse Model of Anti-Obesity Effects ofCurrent issues in molecular biology · 2023Article
- Fermented Foods in the Management of Obesity: Mechanisms of Action and Future Challenges.International journal of molecular sciences · 2023Review
- Metagenomic analysis reveals gut plasmids as diagnosis markers for colorectal cancer.Frontiers in microbiology · 2023Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Japanese traditional cuisine, Washoku, considered to be responsible for increased longevity among the Japanese, comprises various foods fermented with the non-pathogenic fungus Aspergillus oryzae (koji). We have recently revealed that koji contains an abundant amount of glycosylceramide. Intestinal microbes have significant effect on health. However, the effects of koji glycosylceramide on intestinal microbes have not been studied. MATERIALS AND
methodsGlycosylceramide was extracted and purified from koji. C57BL/6N mice were fed a diet containing 1 % purified koji glycosylceramide for 1 week. Nutritional parameters and faecal lipid constituents were analyzed. The intestinal microbial flora of mice on this diet was investigated.
resultsIngested koji glycosylceramide was neither digested by intestinal enzymes nor was it detected in the faeces, suggesting that koji glycosylceramide was digested by the intestinal microbial flora. Intestinal microbial flora that digested koji glycosylceramide had an increased ratio of Blautia coccoides. Stimulation of B. coccoides growth by pure koji glycosylceramide was confirmed in vitro.
conclusionsKoji functions as a prebiotic for B. coccoides through glycosylceramide. Since there are many reports of the effects of B. coccoides on health, an increase in intestinal B. coccoides by koji glycosylceramide might be the connection between Japanese cuisine, intestinal microbial flora, and longevity.
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