ArticleJournal of gastrointestinal oncology2016
Esophagojejunal anastomosis leakage after total gastrectomy for esophagogastric junction adenocarcinoma: options of treatment.
Article in Journal of gastrointestinal oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Intraoperative testing of colorectal anastomosis and the incidence of anastomotic leak: A meta-analysis.Medicine · 2020Pooled it
- Efficacy and safety of anastomotic leak testing in gastric cancer: a randomized controlled trial.Surgical endoscopy · 2023Trial
- Defect Size-Based Comparative Analysis of Treatment Modalities for Esophagojejunal Anastomotic Leakage Following Gastrectomy.Journal of gastric cancer · 2026Article
- Association between Candida esophagitis and esophagojejunal leakage following total gastrectomy: a retrospective cohort study.Langenbeck's archives of surgery · 2025Article
- Predicting Anastomosis or Stump Leakage After Laparoscopic Gastrectomy: A Deep Learning Approach to Intraoperative Image Analysis.Journal of gastric cancer · 2025Article
- A Novel and Feasible Intracorporeal Esophagojejunostomy Anastomosis in Totally Laparoscopic Total Gastrectomy Surgery: Sutureless L-Shape with Endoscopic Assistance (SLEJ).Medicina (Kaunas, Lithuania) · 2025Article
- Fully Covered Self-Expandable Metal Stents for the Treatment of Leak After Oncologic Gastroesophageal Surgery: A Cohort Study.Reviews on recent clinical trials · 2025Article
- Factors associated with anastomotic leak following gastrectomy for gastric adenocarcinoma and its effect on long-term outcomes.Turkish journal of surgery · 2024Article
- Review
- Endoscopic Internal Drainage Achieving Successful Closure of Iatrogenic Pharyngoesophageal Fistula.ACG case reports journal · 2023Article
- The three-tube method via precise interventional placement for esophagojejunal anastomotic fistula after gastrectomy: a single-center experience.World journal of surgical oncology · 2023Article
- Magnetic compression anastomosis for reconstruction of digestive tract after total gastrectomy in beagle model.World journal of gastrointestinal surgery · 2023Article
- Short-term outcomes of a new gastrointestinal decompression tube combined with conservative treatment in patients with esophagojejunal anastomotic leakage after total gastrectomy.Surgical endoscopy · 2023Article
- Predictive Factors for Anastomotic Leakage after Laparoscopic and Open Total Gastrectomy: A Systematic Review.Journal of clinical medicine · 2022Review
- Comparison of Two Endoscopic Therapeutic Interventions as Primary Treatment for Anastomotic Leakages after Total Gastrectomy.Cancers · 2022Article
- Endoscopic internal drainage with double pigtail stents for upper gastrointestinal anastomotic leaks: suitable for all cases?Clinical endoscopy · 2022Article
- Two-stage esophagojejunal anastomosis: An alternative reconstruction in emergency gastrectomy for high-risk gastric cancer patients.SAGE open medical case reports · 2022Article
- Letter to Editor of Annals of Surgical Oncology Concerning "Esophagectomy or Total Gastrectomy for Siewert 2 Gastroesophageal Junction (GEJ) Adenocarcinoma? A Registry-Based Analysis".Annals of surgical oncology · 2022Article
- Pancreatic enzymatic mediastinitis followed by total gastrectomy with splenectomy: report of two cases.Surgical case reports · 2021Article
- Endoscopic closure of jejunal perforation in altered anatomy using a detachable endoloop.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEsophagojejunal anastomosis leakage after total gastrectomy (TG) for esophagogastric junction (EGJ) adenocarcinoma (ADC) constitutes one of the most serious and sometimes life-threatening complications. Management remains controversial and still challenging.
methodsA total of 198 patients operated for type I and II EGJ ADC were reviewed. Diagnosis of leakage was based on a combination of clinical and radiological findings. It was classified including objective endoscopic and clinical parameters requiring different type of treatment.
resultsAnastomotic leakage was diagnosed in 14 patients (7%). Two cases recovered with conservative therapy. Six cases underwent endoscopy with clips placement in 2 and partially covered self-expandable metal stent placement in 4. Other two cases underwent reoperation with reconstruction of anastomosis and primary repair respectively. In the last four cases emergency surgery with total esophagectomy and diversion was required. Mortality occurred only in 3 of these patients and overall treatment was successful in 11 patients (78.5%).
conclusionsNo consensus has been reached on the best method of esophagojejunal anastomosis leakage management and the rate of failure remains significant. Different options of treatment are available but early detection and multidisciplinary approaches are the keys to obtain successful results irrespective of the employed strategy.
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