Observational studyInternational journal of chronic obstructive pulmonary disease2016
Community-acquired pneumonia and survival of critically ill acute exacerbation of COPD patients in respiratory intensive care units.
Observational study in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of pneumonia on the outcomes of acute exacerbation of chronic obstructive pulmonary disease: a systematic review and meta-analysis.BMC pulmonary medicine · 2024Pooled it
- Bacterial Pneumonia and Acute Kidney Injury: Association and Impact on Outcomes of Patients Hospitalized for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) in the United States.The open respiratory medicine journal · 2026Article
- Delta Neutrophil Index and Other Hematologic Parameters in Acute Exacerbations of COPD: A Retrospective Study.Canadian respiratory journal · 2025Article
- Nomograms for Predicting High Hospitalization Costs and Prolonged Stay among Hospitalized Patients with pAECOPD.Canadian respiratory journal · 2024Observational
- Risk factors for hyponatremia in acute exacerbation chronic obstructive pulmonary disease (AECOPD): a multicenter cross-sectional study.BMC pulmonary medicine · 2023Article
- The association of delta neutrophil index with the prognosis of acute exacerbation of chronic obstructive pulmonary disease.BMC pulmonary medicine · 2020Article
- The Impact of Community-acquired Pneumonia on Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients as Regards In-hospital Complications and Early Readmission.The open respiratory medicine journal · 2020Article
- Community-acquired pneumonia and survival of critically ill acute exacerbation of COPD patients in respiratory intensive care units.International journal of chronic obstructive pulmonary disease · 2017Article
- Eosinopenia Predicting Long-term Mortality in Hospitalized Acute Exacerbation of COPD Patients with Community-acquired Pneumonia-A Retrospective Analysis.International journal of chronic obstructive pulmonary diseaseArticle
- Serum procalcitonin and C-reactive protein in the evaluation of bacterial infection in generalized pustular psoriasis.Anais brasileiros de dermatologiaArticle
- Early readmission and mortality in acute exacerbation of chronic obstructive pulmonary disease with community-acquired pneumonia.Chronic respiratory diseaseArticle
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to appraise the effect of community-acquired pneumonia (CAP) on inhospital mortality in critically ill acute exacerbation of COPD (AECOPD) patients admitted to a respiratory intensive care unit. PATIENTS AND
methodsA retrospective observational study was performed. Consecutive critically ill AECOPD patients receiving treatment in a respiratory intensive care unit were reviewed from September 1, 2012, to August 31, 2015. Categorical variables were analyzed using chi-square tests, and continuous variables were analyzed by Mann-Whitney U-test. Kaplan-Meier analysis was used to assess the association of CAP with survival of critically ill AECOPD patients for univariate analysis. Cox's proportional hazards regression model was performed to identify risk factors for multivariate analysis.
resultsA total of 80 consecutive eligible individuals were reviewed. These included 38 patients with CAP and 42 patients without CAP. Patients with CAP had a higher inhospital rate of mortality than patients without CAP (42% vs 33.3%, P<0.05). Kaplan-Meier survival analysis showed that patients with CAP had a worse survival rate than patients without CAP (P<0.05). Clinical characteristics, including Acute Physiology and Chronic Health Evaluation II (APACHE II) score, C-reactive protein, and CAP, were found to be closely associated with survival of AECOPD individuals. Further multivariate Cox regression analysis confirmed that CAP and APACHE II were independent risk factors for inhospital mortality in critically ill AECOPD patients (CAP: hazard ratio, 5.29; 95% CI, 1.50-18.47, P<0.01 and APACHE II: hazard ratio, 1.20; 95% CI, 1.06-1.37, P<0.01).
conclusionCAP may be an independent risk factor for higher inhospital mortality in critically ill AECOPD patients.
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