Evidence map›Paper›PMID 27562867›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2016

Metabolic demands of neural-hemodynamic associated and disassociated areas in brain.

Basavaraju G Sanganahalli, Peter Herman, Douglas L Rothman, Hal Blumenfeld, Fahmeed Hyder

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Baseline electrophysiology versus oxidative metabolism as traits of inter-network differences in neurometabolic association.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  2. Article
  3. mTOR inhibition enhances synaptic and mitochondrial function in Alzheimer's disease in an APOE genotype-dependent manner.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  4. Mapping oxidative metabolism in the human brain with calibrated fMRI in health and disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  5. High-resolution relaxometry-based calibrated fMRI in murine brain: Metabolic differences between awake and anesthetized states.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
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  13. Local oxygen homeostasis during various neuronal network activity states in the mouse hippocampus.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
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  15. Evaluating the gray and white matter energy budgets of human brain function.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Basavaraju G SanganahalliMagnetic Resonance Research Center (MRRC), Yale University, New Haven, USA Quantitative Neuroscience with Magnetic Resonance (QNMR) Core Center, Yale University, New Haven, USA Department of Radiology and Biomedical Imaging, Yale University, New Haven, USA basavaraju.ganganna@yale.edu fahmeed.hyder@yale.edu.
Peter HermanMagnetic Resonance Research Center (MRRC), Yale University, New Haven, USA Quantitative Neuroscience with Magnetic Resonance (QNMR) Core Center, Yale University, New Haven, USA Department of Radiology and Biomedical Imaging, Yale University, New Haven, USA.
Douglas L RothmanMagnetic Resonance Research Center (MRRC), Yale University, New Haven, USA Quantitative Neuroscience with Magnetic Resonance (QNMR) Core Center, Yale University, New Haven, USA Department of Radiology and Biomedical Imaging, Yale University, New Haven, USA Department of Biomedical Engineering, Yale University, New Haven, USA.
Hal BlumenfeldQuantitative Neuroscience with Magnetic Resonance (QNMR) Core Center, Yale University, New Haven, USA Department of Neurology, Yale University, New Haven, USA Department of Neurobiology, Yale University, New Haven, USA.
Fahmeed HyderMagnetic Resonance Research Center (MRRC), Yale University, New Haven, USA Quantitative Neuroscience with Magnetic Resonance (QNMR) Core Center, Yale University, New Haven, USA Department of Radiology and Biomedical Imaging, Yale University, New Haven, USA Department of Biomedical Engineering, Yale University, New Haven, USA.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NeurophysiologicP30NS052519 · NINDS · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED · 2007 to 2017
$6.7M
Energetics of Neuronal Populations by fMRIR01MH067528 · NIMH · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED · 2002 to 2021
$5.9M
Remote effects of focal hippocampal seizures on neocortical functionR01NS066974 · NINDS · YALE UNIVERSITY · PI HAL BLUMENFELD · 2011 to 2026
$5.5M
13C MRS Studies of Brain Mitochondrial Metabolism in Insulin ResistanceR01NS087568 · NINDS · YALE UNIVERSITY · PI PETERSEN, KITT F, ROTHMAN, DOUGLAS LYLE · 2014 to 2018
$2.1M
NCATS NIH HHS UL1 TR001863NIMH NIH HHS R01 MH067528NINDS NIH HHS P30 NS052519NINDS NIH HHS R01 NS066974NINDS NIH HHS R01 NS087568
6 · The paper itself

Abstract

Interpretation of regional blood oxygenation level-dependent (BOLD) responses in functional magnetic resonance imaging (fMRI) is contingent on whether local field potential (LFP) and multi-unit activity (MUA) is either dissociated or associated. To examine whether neural-hemodynamic associated and dissociated areas have different metabolic demands, we recorded sensory-evoked responses of BOLD signal, blood flow (CBF), and blood volume (CBV), which with calibrated fMRI provided oxidative metabolism (CMR

Indexed as

Functional NeuroimagingMagnetic Resonance ImagingAnimalsBlood Flow VelocityCerebrovascular CirculationElectric StimulationEvoked Potentials, SomatosensoryHemodynamicsLaser-Doppler FlowmetryMaleNeuronsOxygen ConsumptionRatsRats, Sprague-DawleySomatosensory CortexVentral Thalamic NucleiGlutamateneuroenergeticsneurometabolicneurovascularspike rate

Identifiers

PMID27562867
PMCPMC5076793
OpenAlexW2509831721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.