ArticleFunctional & integrative genomics2017
Water-deficit stress-responsive microRNAs and their targets in four durum wheat genotypes.
Article in Functional & integrative genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 41 citations in OpenAlex.
- Rice and shine: a review of miRNA-mediated responses to abiotic stress inFrontiers in plant science · 2026Review
- Plant Tolerance to Drought Stress with Emphasis on Wheat.Plants (Basel, Switzerland) · 2023Review
- Integrated analysis of miRNAome transcriptome and degradome reveals miRNA-target modules governing floral florescence development and senescence across early- and late-flowering genotypes in tree peony.Frontiers in plant science · 2022Article
- Small RNA, Transcriptome and Degradome Analysis of the Transgenerational Heat Stress Response Network in Durum Wheat.International journal of molecular sciences · 2021Article
- Nitrogen Starvation-Responsive MicroRNAs Are Affected by Transgenerational Stress in Durum Wheat Seedlings.Plants (Basel, Switzerland) · 2021Article
- Small RNAs and their targets are associated with the transgenerational effects of water-deficit stress in durum wheat.Scientific reports · 2021Article
- Identification, evolution, expression, and docking studies of fatty acid desaturase genes in wheat (Triticum aestivum L.).BMC genomics · 2020Article
- Multi-Omics Analysis of Small RNA, Transcriptome, and Degradome inInternational journal of molecular sciences · 2020Article
- Integrated Analysis of Small RNA, Transcriptome, and Degradome Sequencing Reveals the Water-Deficit and Heat Stress Response Network in Durum Wheat.International journal of molecular sciences · 2020Article
- Epigenetics: possible applications in climate-smart crop breeding.Journal of experimental botany · 2020Review
- Transgenerational Effects of Water-Deficit and Heat Stress on Germination and Seedling Vigour-New Insights from Durum Wheat microRNAs.Plants (Basel, Switzerland) · 2020Article
- Genotypic performance of Australian durum under single and combined water-deficit and heat stress during reproduction.Scientific reports · 2019Article
- MicroRNAs in durum wheat seedlings under chronic and short-term nitrogen stress.Functional & integrative genomics · 2018Article
- Identification of Blueberry miRNAs and Their Targets Based on High-Throughput Sequencing and Degradome Analyses.International journal of molecular sciences · 2018Article
- Identification and characterization of durum wheat microRNAs in leaf and root tissues.Functional & integrative genomics · 2017Article
- microRNAs differentially modulated in response to heat and drought stress in durum wheat cultivars with contrasting water use efficiency.Functional & integrative genomics · 2017Article
- Abiotic stress miRNomes in the Triticeae.Functional & integrative genomics · 2017Review
- Drought-inducible expression of Hv-miR827 enhances drought tolerance in transgenic barley.Functional & integrative genomics · 2017Article
- MicroRNAs in model and complex organisms.Functional & integrative genomics · 2017Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) guide regulation at the post-transcriptional level by inducing messenger RNA (mRNA) degradation or translational inhibition of their target protein-coding genes. Durum wheat miRNAs may contribute to the genotypic water-deficit stress response in different durum varieties. Further investigation of the interactive miRNA-target regulatory modules and experimental validation of their response to water stress will contribute to our understanding of the small RNA-mediated molecular networks underlying stress adaptation in durum wheat. In this study, a comprehensive genome-wide in silico analysis using the updated Triticum transcriptome assembly identified 2055 putative targets for 113 conserved durum miRNAs and 131 targets for four novel durum miRNAs that putatively contribute to genotypic stress tolerance. Predicted mRNA targets encode various transcription factors, binding proteins and functional enzymes, which play vital roles in multiple biological pathways such as hormone signalling and metabolic processes. Quantitative PCR profiling further characterised 43 targets and 5 miRNAs with stress-responsive and/or genotype-dependent differential expression in two stress-tolerant and two stress-sensitive durum genotypes subjected to pre-anthesis water-deficit stress. Furthermore, a 5' RLM-RACE approach validated nine mRNA targets cleaved by water-deficit stress-responsive miRNAs, which, to our knowledge, has not been previously reported in durum wheat. The present study provided experimental evidence of durum miRNAs and target genes in response to water-deficit stress in contrasting durum varieties, providing new insights into the regulatory roles of the miRNA-guided RNAi mechanism underlying stress adaptation in durum wheat.
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