ArticlePlant cell reports2016
Drastic anthocyanin increase in response to PAP1 overexpression in fls1 knockout mutant confers enhanced osmotic stress tolerance in Arabidopsis thaliana.
Article in Plant cell reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 47 citations in OpenAlex.
- A histone deacetylase complex regulates anthocyanin biosynthesis during normal plant growth and development and in response to jasmonate.Plant communications · 2026Article
- Article
- GHCYP706A7 governs anthocyanin biosynthesis to mitigate ROS under alkali stress in cotton.Plant cell reports · 2025Article
- For a Colorful Life: Recent Advances in Anthocyanin Biosynthesis during Leaf Senescence.Biology · 2024Review
- VvWRKY5 positively regulates wounding-induced anthocyanin accumulation in grape by interplaying with VvMYBA1 and promoting jasmonic acid biosynthesis.Horticulture research · 2024Article
- Mutation in BrFLS encoding flavonol synthase induced anthocyanin accumulation in Chinese cabbage.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Genome-Wide Identification of PAP1 Direct Targets in Regulating Seed Anthocyanin Biosynthesis inInternational journal of molecular sciences · 2023Article
- The Role of Anthocyanins in Plant Tolerance to Drought and Salt Stresses.Plants (Basel, Switzerland) · 2023Review
- The Blinin Accumulation Promoted by CbMYB32 Involved inInternational journal of molecular sciences · 2023Article
- Genome-wide analysis and transcriptional reprogrammings of MYB superfamily revealed positive insights into abiotic stress responses and anthocyanin accumulation in Carthamus tinctorius L.Molecular genetics and genomics : MGG · 2022Article
- VipariNama: RNA viral vectors to rapidly elucidate the relationship between gene expression and phenotype.Plant physiology · 2021Article
- MYB-Mediated Regulation of Anthocyanin Biosynthesis.International journal of molecular sciences · 2021Review
- Growth Performance Can Be Increased Under High Nitrate and High Salt Stress Through Enhanced Nitrate Reductase Activity inFrontiers in plant science · 2021Article
- Changes at a Critical Branchpoint in the Anthocyanin Biosynthetic Pathway Underlie the Blue to Orange Flower Color Transition inFrontiers in plant science · 2021Article
- Tree peony variegated flowers show a small insertion in the F3'H gene of the acyanic flower parts.BMC plant biology · 2020Article
- RrMYB5- and RrMYB10-regulated flavonoid biosynthesis plays a pivotal role in feedback loop responding to wounding and oxidation in Rosa rugosa.Plant biotechnology journal · 2019Article
- De novo transcriptome sequencing of radish (Raphanus sativus L.) fleshy roots: analysis of major genes involved in the anthocyanin synthesis pathway.BMC molecular and cell biology · 2019Article
- Dual role of SND1 facilitates efficient communication between abiotic stress signalling and normal growth in Arabidopsis.Scientific reports · 2018Article
- Dissecting the 'bacon and eggs' phenotype: transcriptomics of post-anthesis colour change in Lotus.Annals of botany · 2017Article
- Synergetic effect of the Onion CHI gene on the PAP1 regulatory gene for enhancing the flavonoid profile of tomato skin.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messagepap1 - D/fls1ko double mutant plants that produce substantial amounts of anthocyanin show tolerance to abiotic stress. Anthocyanins are flavonoids that are abundant in various plants and have beneficial effects on both plants and humans. Many genes in flavonoid biosynthetic pathways have been identified, including those in the MYB-bHLH-WD40 (MBW) complex. The MYB gene Production of Anthocyanin Pigment 1 (PAP1) plays a particularly important role in anthocyanin accumulation. PAP1 expression in many plant systems strongly increases anthocyanin levels, resulting in a dark purple color in many plant organs. In this study, we generated double mutant plants that harbor fls1ko in the pap1-D background (i.e., pap1-D/fls1ko plants), to examine whether anthocyanins can be further enhanced by blocking flavonol biosynthesis under PAP1 overexpression. We also wanted to examine whether the increased anthocyanin levels contribute to defense against osmotic stresses. The pap1-D/fls1ko mutants accumulated higher anthocyanin levels than pap1-D plants in both control and sucrose-treated conditions. However, flavonoid biosynthesis genes were slightly down-regulated in the pap1-D/fls1ko seedlings as compared to their expression in pap1-D seedlings. We also report the performance of pap1-D/fls1ko seedlings in response to plant osmotic stresses.
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