Evidence map›Paper›PMID 27562181›Full record

ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2017

A new experimentally validated formula to calculate the QT interval in the presence of left bundle branch block holds true in the clinical setting.

Harilaos Bogossian, Gerrit Frommeyer, Ilias Ninios, Eleni Pechlivanidou, Fuad Hasan, Quy Suu Nguyen, Dejan Mijic, Axel Kloppe, Zana Karosiene, Artak Margkarian and 7 more

Abstract readValidation Study
In one paragraph

Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. QTc interval measurement in patients with right bundle branch block: A practical method.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
    Article
  3. QTc evaluation in patients with bundle branch block.International journal of cardiology. Heart & vasculature · 2020
    Review
  4. Observational
  5. Novel approach to discriminate left bundle branch block from nonspecific intraventricular conduction delay using pacing-induced functional left bundle branch block.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2018
    Article
  6. Incidence and outcomes of long QTc in acute medical admissions.International journal of clinical practice · 2018
    Observational
  7. Observational
  8. Cutting off half of QRS duration can cause overcorrection of QT interval in left bundle branch block.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2017
    Article
  9. Reply: QT interval measurements in patients with left bundle branch block. There is yet more to learn about repolarization.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2017
    Article
  10. A new experimentally validated formula to calculate the QT interval in the presence of left bundle branch block holds true in the clinical setting.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Harilaos BogossianMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Gerrit FrommeyerDivision of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
Ilias NiniosMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Eleni PechlivanidouMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Fuad HasanMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Quy Suu NguyenMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Dejan MijicMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Axel KloppeMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Zana KarosieneMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Artak MargkarianMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Dirk BandorskiMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Dominik SchultesMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Damir ErkapicMedical Clinic I, Department of Cardiology, Justus-Liebig University of Giessen, Giessen, Germany.
Melchior SeyfarthDepartment of Cardiology, University Witten/Herdecke, Witten, Germany.
Bernd LemkeMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Lars EckardtDivision of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
Markus ZarseMärkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Lüdenscheid, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe evaluation of the QT interval in the presence of left bundle branch block (LBBB) is associated with the challenge to discriminate native QT interval from the prolongation due to the increase in QRS duration. The newest formula to evaluate QT interval in the presence of LBBB suggests: modified QT during LBBB = measured QT interval minus 50% of LBBB duration. The purpose of this study is therefore to validate the abovementioned formula in the clinical setting.

methodsValidation in two separate groups of patients: Patients who alternated between narrow QRS and intermittent LBBB and patients with narrow QRS who developed LBBB after transcatheter aortic valve implantation (TAVI).

resultsThe acquired mean native QTc intervals and those calculated by the presented formula displayed no significant differences (p > .99 and p > .75).

conclusionsIn this study we proved for the first time the validity and applicability of the experimentally acquired formula for the evaluation of the QT interval in the presence of LBBB in a clinical setting.

Indexed as

Bundle-Branch BlockBundle of HisElectrocardiographyHumansReproducibility of ResultsRetrospective StudiesRisk FactorsTreatment OutcomeJT intervalleft bundle brunch blocklong QTQT formulaQT intervalQT prolongation

Identifiers

PMID27562181
PMCPMC6931597

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.