ArticleBlood purification2016
Precision Continuous Renal Replacement Therapy and Solute Control.
Article in Blood purification, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference.Kidney international · 2020 · on this mapGuideline
- [Performance evaluation of different filtration fractions during daytime continuous renal replacement therapy].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025Trial
- Lactate in acute kidney injury: pathobiology, risk stratification, and clinical interpretation.Renal failure · 2026Review
- Extracorporeal therapies in the management of paraquat poisoning: a comprehensive review of current evidence.Annals of medicine · 2026Review
- Depletion of Uric Acid by Continuous Kidney Replacement Therapy.Blood purification · 2026Article
- Program of quality improvement for extracorporeal blood purification therapies in the intensive care unit.Journal of clinical monitoring and computing · 2026Review
- Association between obesity and kidney outcomes in critically ill patients with acute kidney injury receiving continuous renal replacement therapy: a secondary analysis of the multicenter CRRTnet study.Critical care (London, England) · 2026Observational
- Renal replacement therapy in intensive care unit: a narrative review.Annals of intensive care · 2026Review
- Use of Oxiris membrane in real-world clinical practice in critical care patients: a multicenter observational study.Journal of anesthesia, analgesia and critical care · 2025Article
- Access recirculation in continuous kidney replacement therapy with regional citrate anticoagulation: a case report and diagnostic insights.BMC nephrology · 2025Article
- Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit.Journal of intensive care · 2025Article
- Interruptions and downtime of continuous renal replacement therapy in critically ill adults: A retrospective observational study.Nursing in critical care · 2025Observational
- Characteristics and outcomes of children ≤ 10 kg receiving continuous kidney replacement therapy: a WE-ROCK study.Pediatric nephrology (Berlin, Germany) · 2025Observational
- The Rationale for Combining Normothermic Liver Machine Perfusion with Continuous Renal Replacement Therapy to Maintain Physiological Perfusate during Ex Vivo Organ Perfusion.Journal of clinical medicine · 2024Article
- Dynamic dosing for continuous renal replacement therapy: Service evaluation of the safety and effectiveness of titrating dose to biochemistry.Journal of the Intensive Care Society · 2024Article
- Coagulation Risk Predicting in Anticoagulant-Free Continuous Renal Replacement Therapy.Blood purification · 2024Article
- Article
- Epidemiology and Outcomes of AKI Treated With Continuous Kidney Replacement Therapy: The Multicenter CRRTnet Study.Kidney medicine · 2023Article
- The landscape of renal replacement therapy in Veterans Affairs Medical Center intensive care units.Renal failure · 2021Article
- Methods for dose quantification in continuous renal replacement therapy: Toward a more precise approach.Artificial organs · 2021Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Continuous renal replacement therapy (CRRT) remains the dominant form of renal support among critically ill patients worldwide. Current clinical practice on CRRT prescription mostly relies on high quality studies suggesting no impact of CRRT dose on critically ill patients' outcomes. Recent clinical practice guidelines have been developed based on these studies recommending a static prescribed CRRT dose of 20-25 ml/kg/h. There is a rationale for renewed attention to CRRT prescription/practice based on the concept of dynamic solute control adapted to the changing clinical needs of critically ill patients. In response, Acute Disease Quality Initiative convened a 17th consensus meeting centered on re-evaluation of CRRT. This work group developed 4 themes focused specifically on CRRT dose prescription, delivery and solute control that were summarized in a series of consensus statements, along with the identification of critical knowledge gaps. CRRT dose prescription and delivery can be based on effluent flow rate. Delivered dose should be routinely monitored to ensure coherence with prescribed dose. CRRT dose should be dynamic, in recognition of between- and within-patient variation in targeted solute control or unintended solute clearance. Quality measures specific for monitoring delivered CRRT dose have been proposed that require further validation, prior to implementation, into the practice of guiding optimal CRRT dosage.
Indexed as
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27562079What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.