Evidence map›Paper›PMID 27561794›Full record

ArticleBMC public health2016

Mortality among tuberculosis patients under DOTS programme: a historical cohort study.

Yeshiwork Beyene, Berhanu Geresu, Assefa Mulu

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In one paragraph

Article in BMC public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yeshiwork BeyeneDepartment of Nursing, College of Medicine and Health Sciences Wollo University, Dessie, Ethiopia.
Berhanu GeresuDepartment of Pharmacy, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia. berhanu.grs@gmail.com.
Assefa MuluDepartment of Pharmacy, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn high human immunodeficiency virus (HIV) prevalence population, tuberculosis (TB) is the leading cause of morbidity and mortality. HIV is driving the TB epidemic in many countries, especially those in sub-Saharan Africa. We assessed the survival time and predictors of mortality among tuberculosis patients under directly observed treatment, short course (DOTS) strategy in Dessie Referral Hospital tuberculosis clinic, Northeast Ethiopia.

methodA historical cohort design was utilized to assess survival time and determinants of mortality. A total of 1260 records of patients who started ant-tuberculosis treatment from January 2006 up to December 2010 were analyzed. Survival curves were estimated using Kaplan-Meier and were compared using the Log-rank test. The Cox proportional hazard model was used to assess the relationship between baseline variables and mortality.

resultsOut of the 1260 registered patients, 117 (9.3 %) died over the entire follow-up period. Among those died, 113 (18 %) were HIV positive and 4 (0.6 %) were HIV negative. The 1260 patients contributed a cumulative total of 634.25 person‑years observation.

conclusionThe mortality of HIV positive tuberculosis patients was higher than those of HIV negative patients and the use of cotrimoxazole preventive therapy increased the survival time of patients.

Indexed as

Directly Observed TherapyAdultAnti-Bacterial AgentsCohort StudiesEthiopiaFemaleHIV SeropositivityHumansMaleMiddle AgedProportional Hazards ModelsReferral and ConsultationTrimethoprim, Sulfamethoxazole Drug CombinationTuberculosisYoung AdultAnti-Bacterial AgentsTrimethoprim, Sulfamethoxazole Drug CombinationDessie Referral HospitalHIVMortalitySurvivalTuberculosis

Identifiers

PMID27561794
PMCPMC5000467

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.