ArticleBiomechanics and modeling in mechanobiology2017
Quantify patient-specific coronary material property and its impact on stress/strain calculations using in vivo IVUS data and 3D FSI models: a pilot study.
Article in Biomechanics and modeling in mechanobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Toward quantitative X-ray elastography of coronary arteries using flexural pulse waves.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Comparison and identification of human coronary plaques with/without erosion using patient-specific optical coherence tomography-based fluid-structure interaction models: a pilot study.Biomechanics and modeling in mechanobiology · 2025Article
- Non-invasive estimation of material properties of normal and dissected human ascending aortasFrontiers in bioengineering and biotechnology · 2025Article
- Patient-Specific Numerical Simulations of Coronary Artery Hemodynamics and Biomechanics: A Pathway to Clinical Use.Cardiovascular engineering and technology · 2024Review
- Measurement of Layer-Specific Mechanical Properties of Intact Blood Vessels Based on Intravascular Optical Coherence Tomography.Cardiovascular engineering and technology · 2023Article
- Combining IVUS + OCT Data, Biomechanical Models and Machine Learning Method for Accurate Coronary Plaque Morphology Quantification and Cap Thickness and Stress/Strain Index Predictions.Journal of functional biomaterials · 2023Article
- Long-term prognostic impact of paravalvular leakage on coronary artery disease requires patient-specific quantification of hemodynamics.Scientific reports · 2022Article
- Image-Based Finite Element Modeling Approach for Characterizing In Vivo Mechanical Properties of Human Arteries.Journal of functional biomaterials · 2022Review
- Predicting Coronary Stenosis Progression Using Plaque Fatigue From IVUS-Based Thin-Slice Models: A Machine Learning Random Forest Approach.Frontiers in physiology · 2022Article
- Medical Image-Based Computational Fluid Dynamics and Fluid-Structure Interaction Analysis in Vascular Diseases.Frontiers in bioengineering and biotechnology · 2022Review
- Multi-patient study for coronary vulnerable plaque model comparisons: 2D/3D and fluid-structure interaction simulations.Biomechanics and modeling in mechanobiology · 2021Article
- Predicting plaque vulnerability change using intravascular ultrasound + optical coherence tomography image-based fluid-structure interaction models and machine learning methods with patient follow-up data: a feasibility study.Biomedical engineering online · 2021Article
- A prediction tool for plaque progression based on patient-specific multi-physical modeling.PLoS computational biology · 2021Article
- Quantifying Patient-SpecificFrontiers in physiology · 2021Article
- A pragmatic approach to understand peripheral artery lumen surface stiffness due to plaque heterogeneity.Computer methods in biomechanics and biomedical engineering · 2019Article
- Combining IVUS and Optical Coherence Tomography for More Accurate Coronary Cap Thickness Quantification and Stress/Strain Calculations: A Patient-Specific Three-Dimensional Fluid-Structure Interaction Modeling Approach.Journal of biomechanical engineering · 2018Article
- Fluid-structure interaction models based on patient-specific IVUS at baseline and follow-up for prediction of coronary plaque progression by morphological and biomechanical factors: A preliminary study.Journal of biomechanics · 2018Article
- Mechanical Characterization of the Vessel Wall by Data Assimilation of Intravascular Ultrasound Studies.Frontiers in physiology · 2018Article
- Coronary Atherosclerotic Vulnerable Plaque: Current Perspectives.Journal of the American Heart Association · 2017Review
- Radial Wall Strain Assessment From AI-Assisted Angiography: Feasibility and Agreement With OCT as Reference Standard.Journal of the Society for Cardiovascular Angiography & InterventionsArticle
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Computational models have been used to calculate plaque stress and strain for plaque progression and rupture investigations. An intravascular ultrasound (IVUS)-based modeling approach is proposed to quantify in vivo vessel material properties for more accurate stress/strain calculations. In vivo Cine IVUS and VH-IVUS coronary plaque data were acquired from one patient with informed consent obtained. Cine IVUS data and 3D thin-slice models with axial stretch were used to determine patient-specific vessel material properties. Twenty full 3D fluid-structure interaction models with ex vivo and in vivo material properties and various axial and circumferential shrink combinations were constructed to investigate the material stiffness impact on stress/strain calculations. The approximate circumferential Young's modulus over stretch ratio interval [1.0, 1.1] for an ex vivo human plaque sample and two slices (S6 and S18) from our IVUS data were 1631, 641, and 346 kPa, respectively. Average lumen stress/strain values from models using ex vivo, S6 and S18 materials with 5 % axial shrink and proper circumferential shrink were 72.76, 81.37, 101.84 kPa and 0.0668, 0.1046, and 0.1489, respectively. The average cap strain values from S18 material models were 150-180 % higher than those from the ex vivo material models. The corresponding percentages for the average cap stress values were 50-75 %. Dropping axial and circumferential shrink consideration led to stress and strain over-estimations. In vivo vessel material properties may be considerably softer than those from ex vivo data. Material stiffness variations may cause 50-75 % stress and 150-180 % strain variations.
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