ArticleScientific reports2016
The influence of the aortic valve angle on the hemodynamic features of the thoracic aorta.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Comparison of compressed sensing and conventional 4D flow MRI for turbulent kinetic energy assessment in healthy participants and patients with aortic stenosis.Scientific reports · 2026Article
- Integrated Assessment of Wall Shear Stress-Related Hemodynamic Parameters in Abdominal Aortic Aneurysms: A Retrospective Cross-Sectional Study on Ruptured Cases.International journal for numerical methods in biomedical engineering · 2026Article
- Influence of Coronary Flow and Left Ventricular Outflow Tract Velocity on LDL Accumulation and Calcification in Aortic Valve Leaflets.Biomechanics (Basel, Switzerland) · 2025Article
- Rapid wall shear stress prediction for aortic aneurysms using deep learning: a fast alternative to CFD.Medical & biological engineering & computing · 2025Article
- Intra- and interobserver reliability in measuring aortic root rotation with cardiac magnetic resonance imaging.Cardiovascular diagnosis and therapy · 2024Article
- Design and Analysis of a Polymeric Left Ventricular Simulator via Computational Modelling.Biomimetics (Basel, Switzerland) · 2024Article
- Asymmetry of flow in aortic root and its application in hypertrophic obstructive cardiomyopathy.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Radiomics-based aortic flow profile characterization with 4D phase-contrast MRI.Frontiers in cardiovascular medicine · 2023Article
- Fully Three-Dimensional Hemodynamic Characterization of Altered Blood Flow in Bicuspid Aortic Valve Patients With Respect to Aortic Dilatation: A Finite Element Approach.Frontiers in cardiovascular medicine · 2022Article
- The impact of shape uncertainty on aortic-valve pressure-drop computations.International journal for numerical methods in biomedical engineering · 2021Article
- Blood flow dynamics with four-dimensional flow cardiovascular magnetic resonance in patients with aortic stenosis before and after transcatheter aortic valve replacement.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Article
- Bicuspid aortic valve morphology and aortic valvular outflow jets: an experimental analysis using an MRI-compatible pulsatile flow circulation system.Scientific reports · 2021Article
- Prediction of Stress Map in Ascending Aorta - Optimization of the Coaxial Position in Transcatheter Aortic Valve Replacement.Arquivos brasileiros de cardiologia · 2020Article
- Is there any association between aortic root rotation angle and aortic dissection?Indian journal of thoracic and cardiovascular surgery · 2020Article
- Aortic valvular imaging with cardiovascular magnetic resonance: seeking for comprehensiveness.The British journal of radiology · 2019Review
- Model-Based Therapy Planning Allows Prediction of Haemodynamic Outcome after Aortic Valve Replacement.Scientific reports · 2017Article
- Estimating the irreversible pressure drop across a stenosis by quantifying turbulence production using 4D Flow MRI.Scientific reports · 2017Article
- Influence of the tilt angle of Percutaneous Aortic Prosthesis on Velocity and Shear Stress FieldsArquivos brasileiros de cardiologiaArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the first observation of a helical flow pattern in aortic blood flow, the existence of helical blood flow has been found to be associated with various pathological conditions such as bicuspid aortic valve, aortic stenosis, and aortic dilatation. However, an understanding of the development of helical blood flow and its clinical implications are still lacking. In our present study, we hypothesized that the direction and angle of aortic inflow can influence helical flow patterns and related hemodynamic features in the thoracic aorta. Therefore, we investigated the hemodynamic features in the thoracic aorta and various aortic inflow angles using patient-specific vascular phantoms that were generated using a 3D printer and time-resolved, 3D, phase-contrast magnetic resonance imaging (PC-MRI). The results show that the rotational direction and strength of helical blood flow in the thoracic aorta largely vary according to the inflow direction of the aorta, and a higher helical velocity results in higher wall shear stress distributions. In addition, right-handed rotational flow conditions with higher rotational velocities imply a larger total kinetic energy than left-handed rotational flow conditions with lower rotational velocities.
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