ArticleEnvironmental health perspectives2017
Associations between Unconventional Natural Gas Development and Nasal and Sinus, Migraine Headache, and Fatigue Symptoms in Pennsylvania.
Article in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.
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Who cites it
58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- A Systematic Review of the Epidemiologic Literature Assessing Health Outcomes in Populations Living near Oil and Natural Gas Operations: Study Quality and Future Recommendations.International journal of environmental research and public health · 2019Pooled it
- Exploring the endocrine activity of air pollutants associated with unconventional oil and gas extraction.Environmental health : a global access science source · 2018Pooled it
- Exposure to coal-fired power plant emissions, unconventional natural gas development, and salivary miRNA profiles and asthma in children.Environmental research · 2026Article
- The Fire That Does Not Go Out: The Neglected Costs of Gas Flaring in Nigeria.International journal of environmental research and public health · 2026Article
- Monitoring and Modeling Population Exposures to Air Pollutants from Oil and Gas Development: Part 1. Predictive, Source-Oriented Modeling and Measurements to Evaluate Community Exposures to Air Pollutants and Noise from Unconventional Oil and Gas Development.Research report (Health Effects Institute) · 2026Article
- Article
- The health burden and racial-ethnic disparities of air pollution from the major oil and gas lifecycle stages in the United States.Science advances · 2025Article
- Associations of environmental and community features with radiologic sinus inflammation in Pennsylvania, USA.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Sex differences in healthcare utilization for chronic rhinosinusitis: a prospective cohort study.BMC health services research · 2025Article
- Cumulative Human Health Risk Assessment of Regional Ozone and Volatile Organic Compounds from Unconventional Oil and Gas Sites in Colorado's Front Range.Environmental health perspectives · 2025Article
- The Environment and Headache: a Narrative Review.Current environmental health reports · 2024Review
- The human health effects of unconventional oil and gas development (UOGD): A scoping review of epidemiologic studies.Canadian journal of public health = Revue canadienne de sante publique · 2024Article
- Associations between environmental perchlorate, nitrate, and thiocyanate exposure and severe headache or migraine: a cross-sectional, population-based analysis.Frontiers in neurology · 2024Article
- Environmental Justice: Where It Has Been, and Where It Might Be Going.Annual review of public health · 2023Review
- Outcomes of the Halliburton Loophole: Chemicals regulated by the Safe Drinking Water Act in US fracking disclosures, 2014-2021.Environmental pollution (Barking, Essex : 1987) · 2023Article
- Health Symptoms and Proximity to Active Multi-Well Unconventional Oil and Gas Development Sites in the City and County of Broomfield, Colorado.International journal of environmental research and public health · 2023Article
- Air Pollution and Headache Disorders.Annals of Indian Academy of Neurology · 2022Article
- Assessing Exposure to Unconventional Oil and Gas Development: Strengths, Challenges, and Implications for Epidemiologic Research.Current environmental health reports · 2022Review
- The association of unconventional natural gas development with diagnosis and treatment of internalizing disorders among adolescents in Pennsylvania using electronic health records.Environmental research · 2022Article
- Spatiotemporal Correlation Analysis of Hydraulic Fracturing and Stroke in the United States.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundUnconventional natural gas development (UNGD) produces environmental contaminants and psychosocial stressors. Despite these concerns, few studies have evaluated the health effects of UNGD.
objectivesWe investigated associations between UNGD activity and symptoms in a cross-sectional study in Pennsylvania.
methodsWe mailed a self-administered questionnaire to 23,700 adult patients of the Geisinger Clinic. Using standardized and validated questionnaire items, we identified respondents with chronic rhinosinusitis (CRS), migraine headache, and fatigue symptoms. We created a summary UNGD activity metric that incorporated well phase, location, total depth, daily gas production and inverse distance-squared to patient residences. We used logistic regression, weighted for sampling and response rates, to assess associations between quartiles of UNGD activity and outcomes, both alone and in combination.
resultsThe response rate was 33%. Of 7,785 study participants, 1,850 (24%) had current CRS symptoms, 1,765 (23%) had migraine headache, and 1,930 (25%) had higher levels of fatigue. Among individuals who met criteria for two or more outcomes, adjusted odds ratios for the highest quartile of UNGD activity compared with the lowest were [OR (95% CI)] 1.49 (0.78, 2.85) for CRS plus migraine, 1.88 (1.08, 3.25) for CRS plus fatigue, 1.95 (1.18, 3.21) for migraine plus fatigue, and 1.84 (1.08, 3.14) for all three outcomes together. Significant associations were also present in some models of single outcomes.
conclusionsThis study provides evidence that UNGD is associated with nasal and sinus, migraine headache, and fatigue symptoms in a general population representative sample. Citation: Tustin AW, Hirsch AG, Rasmussen SG, Casey JA, Bandeen-Roche K, Schwartz BS. 2017. Associations between unconventional natural gas development and nasal and sinus, migraine headache, and fatigue symptoms in Pennsylvania. Environ Health Perspect 125:189-197; http://dx.doi.org/10.1289/EHP281.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.