Personal mastery attenuates the adverse effect of frailty on declines in physical function of older people: A 6-year population-based cohort study.

Personal mastery is an important determinant in shaping physical health across middle and late life. The modified effect of mastery on relation between frailty and adverse health outcome remains unclear. The main purpose of this study was to evaluate the prognostic role of mastery on frailty among older people by using a nationwide representative population-based cohort. In total, 715 community-dwelling participants aged 54 years and over recruited in 2000 and received second visit 6 years later. Personal mastery was represented by the Pearlin mastery score, and frailty was defined by modified Fried criteria. Multivariate generalized linear mixed analysis was used to examine the association interaction between frailty and Pearlin mastery scores for activities of daily living decline. Overall, prevalence of frailty and prefrail were 9.7% and 48.8%. In a 6-year period, 94 participants (13.1%) experienced functional decline. Compared with function nondecliners, function decliners had greater proportion of frailty (26.6% vs 7.1%; P < 0.001) and lesser mastery score (17.2 vs 18.7; P < 0.001). After adjusting with basic demography, healthy behavior, cognitive function, and multimorbidity, frailty status and mastery were significantly interacted (coefficient estimate: -0.80, standard error: 0.23, P = 0.001). The negative coefficient estimate indicated that self-control, that is, self-mastery, may attenuate the adverse effects of frailty on functional outcomes. Similar results were shown when subjects with baseline functional deficits were excluded for analysis. In conclusion, high self-mastery attenuates adverse effects of frailty on functional decline.