Trial reportMedicine2016
The effect of neck-specific exercise with or without a behavioral approach on psychological factors in chronic whiplash-associated disorders: A randomized controlled trial with a 2-year follow-up.
Trial report in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Is the integration of education with exercise beneficial for whiplash-associated disorders? A systematic review and meta-analysis.The Journal of manual & manipulative therapy · 2025Pooled it
- Psychological therapies for the management of chronic pain (excluding headache) in adults.The Cochrane database of systematic reviews · 2020Pooled it
- The role of non-rigid cervical collar in pain relief and functional restoration after whiplash injury: a systematic review and a pooled analysis of randomized controlled trials.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019Pooled it
- Efficacy of neck-specific exercises with and without internet-based support on psychological factors in chronic whiplash-associated disorders: secondary analyses of a randomized controlled trial.Pain medicine (Malden, Mass.) · 2026Trial
- Pain Science Education, Stress Management, and Cognition-Targeted Exercise Therapy in Chronic Whiplash Disorders: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Factors Related to Pain and Disability Outcomes After an Internet-Delivered or Physiotherapist-Led Exercise Program for Individuals With Chronic Whiplash Symptoms: Secondary Analysis of a Randomized Controlled Study.JMIR human factors · 2025Trial
- Psychophysiological responses to a multimodal physiotherapy program in fighter pilots with flight-related neck pain: A pilot trial.PloS one · 2024Trial
- Comparison of high-intensity laser therapy and combination of ultrasound treatment and transcutaneous nerve stimulation in patients with cervical spondylosis: a randomized controlled trial.Lasers in medical science · 2019Trial
- The effect of three exercise approaches on health-related quality of life, and factors associated with its improvement in chronic whiplash-associated disorders: analysis of a randomized controlled trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Trial
- Neck-specific exercise may reduce radiating pain and signs of neurological deficits in chronic whiplash - Analyses of a randomized clinical trial.Scientific reports · 2018Trial
- Effectiveness of percutaneous neuromuscular electrical stimulation for neck pain relief in patients with cervical spondylosis.Medicine · 2018Trial
- Living with ongoing whiplash associated disorders: a qualitative study of individual perceptions and experiences.BMC musculoskeletal disorders · 2017Trial
- Neck-specific exercises with internet-based support compared to neck-specific exercises at a physiotherapy clinic for chronic whiplash-associated disorders: study protocol of a randomized controlled multicentre trial.BMC musculoskeletal disorders · 2017Trial
- The Effect of Neck-Specific Exercise with or Without a Behavioral Approach in Chronic Whiplash-Associated Disorders: A Systematic Review and Meta-Analysis.Muscles (Basel, Switzerland) · 2025Review
- Design of a Health Education Program to Manage Chronic Neck Pain: Protocol for a Development Study.JMIR research protocols · 2024Article
- Fatty infiltrate and neck muscle volume in individuals with chronic whiplash associated disorders compared to healthy controls - a cross sectional case-control study.BMC musculoskeletal disorders · 2023Article
- Assessment from a Biopsychosocial Approach of Flight-Related Neck Pain in Fighter Pilots of Spanish Air Force. An Observational Study.Diagnostics (Basel, Switzerland) · 2022Article
- A Scoping Review of the Evidence regarding Assessment and Management of Psychological Features of Shoulder Pain.Rehabilitation research and practice · 2021Article
- Pathophysiology behind prolonged whiplash associated disorders: study protocol for an experimental study.BMC musculoskeletal disorders · 2019Article
- A narrative review on cervical interventions in adults with chronic whiplash-associated disorder.BMJ open sport & exercise medicine · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the effect of neck-specific exercise with (NSEB) or without (NSE) a behavioural approach and prescribed physical activity (PPA) on general pain disability and psychological factors in chronic whiplash-associated disorders (WAD), grade 2 and 3, with a 2-year follow-up.
methodsA randomized controlled multi-centre study of 3 exercise interventions (NSE, NSEB or PPA) including a 2-year follow-up. A total of 216 volunteers with chronic WAD were recruited and 194 were analyzed, mean age 40.4 (Standard Deviation [SD] 11.4). Measures of general pain disability, pain catastrophizing, anxiety and depression, and kinesiophobia were evaluated at baseline, and 3, 6, 12 and 24 months with linear mixed models.
resultsGeneral pain disability decreased by 28% in the NSEB group from baseline to 3 months (P < 0.001) and the improvements in disability were maintained over time (6, 12 and 24 months P < 0.01) compared to the NSE (P > 0.42) and PPA groups (P > 0.43). Pain catastrophizing decreased in the NSE group from baseline to 6 and 12 months (P < 0.01) and in the NSEB group from baseline to 3 and 24 months (P < 0.01) compared to the PPA group (P > 0.82) that showed no change over time. The NSE group improved in kinesiophobia over time from baseline to12 months (P < 0.01) compared to the NSEB (P = 0.052) and the PPA groups (P > 0.74). Anxiety decreased over time from baseline to 12 and 24 months in the NSE group (P > 0.02), but not in the NSEB (P > 0.25) or the PPA (P > 0.50) groups. The PPA had no effect on general disability or any of the measured psychological factors.
conclusionThis randomised controlled trial with a 2-year follow-up shows that physiotherapist-led neck-specific exercise with or without the addition of a behavioural approach had superior outcome on general disability and most psychological factors compared to the mere prescription of physical activity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.