ArticleEarly human development2016
Gastrostomy tube placement in infants with congenital diaphragmatic hernia: Frequency, predictors, and growth outcomes.
Article in Early human development, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Nutritional management of neonates who undergo major surgery for gastrointestinal disorders: a joint position paper of the Italian Society of Neonatology (SIN), the Italian Society of Pediatric Surgery (SICP), and the Italian Society of Pediatric Nutrition (SINUPE).Italian journal of pediatrics · 2026Guideline
- A clinical consensus guideline for nutrition in infants with congenital diaphragmatic hernia from birth through discharge.Journal of perinatology : official journal of the California Perinatal Association · 2024Guideline
- The challenges of medically complex breastfed children and their families: A systematic review.Maternal & child nutrition · 2021Pooled it
- Article
- Long-term follow-up of patients with congenital diaphragmatic hernia.World journal of pediatric surgery · 2024Review
- Surgical Risk Factors for Delayed Oral Feeding Autonomy in Patients with Left-Sided Congenital Diaphragmatic Hernia.Journal of clinical medicine · 2023Article
- Congenital diaphragmatic hernia.Nature reviews. Disease primers · 2022Review
- Prenatal stomach position and volume in relation to postnatal outcomes in left-sided congenital diaphragmatic hernia.Prenatal diagnosis · 2022Article
- Impact of Gastrostomy Tube Placement on Short-Term Weight Gain in Hospitalized Premature Infants.JPEN. Journal of parenteral and enteral nutrition · 2020Article
- Predictors of Feeding Tube Placement in Infants with Congenital Diaphragmatic Hernia: A Systematic Review and Meta-analysis of Cohort Studies.Journal of Indian Association of Pediatric SurgeonsReview
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundGastrostomy tube (G-tube) placement is a common intervention for newborns with severe feeding difficulties. Infants with congenital diaphragmatic hernia (CDH) are at high risk for feeding problems. Prevalence of G-tube placement and consequent nutritional outcomes of infants with CDH and G-tubes has not been described.
aimsDetermine factors associated with G-tube placement and growth in infants with congenital diaphragmatic hernia. STUDY
designRetrospective cohort study of infants with CDH to evaluate the association of G-tube placement with risk factors using logistic regression. We also assessed the association between growth velocity and G-tube placement and other risk factors using linear regression. SUBJECTS: The subjects of the study were infants with CDH treated at Duke University Medical Center from 1997 to 2013. OUTCOME MEASURES: Weight gain in infants with CDH that had G-tube placement compared to those infants with CDH that did not.
resultOf the 123 infants with CDH, 85 (69%) survived and G-tubes were placed in 25/85 (29%) survivors. On adjusted analysis, extracorporeal membrane oxygenation (OR=11.26 [95% CI: 1.92-65.89]; P=0.01) and proton pump inhibitor use (OR=17.29 [3.98-75.14], P≤0.001) were associated with G-tube placement. Infants without G-tubes had a growth velocity of 6.5g/day (95% CI: 2.5-10.4) more than infants with G-tubes.
conclusionSurvivors with more complex inpatient courses were more likely to receive G-tubes. Further investigation is needed to identify optimal feeding practices for infants with CDH.
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