Evidence map›Paper›PMID 27559493›Full record

ArticleJournal of gastrointestinal & digestive system2015

Increased Incidence of Early Onset Colorectal Cancer in Arizona: A Comprehensive 15-year Analysis of the Arizona Cancer Registry.

Hassan Aziz, Viraj Pandit, Ryan M DiGiovanni, Eric Ohlson, Angelika C Gruessner, Jana Jandova, Valentine N Nfonsam

Open access · hybridAbstract read
In one paragraph

Article in Journal of gastrointestinal & digestive system, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Does it matter where you get your surgery for colorectal cancer?International journal of colorectal disease · 2019
    Observational
  5. Article
  6. Article
  7. Gene Expression Analysis of Sporadic Early-Onset Rectal Adenocarcinoma.Gastrointestinal cancer : research & therapy · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hassan AzizDepartment of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ.
Viraj PanditDepartment of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ.
Ryan M DiGiovanniDepartment of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ.
Eric OhlsonDepartment of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ.
Angelika C GruessnerDepartment of Epidemiology and Biostatistics Division, University of Arizona, Tucson, AZ.
Jana JandovaDepartment of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ; Department of Pathology, University of Arizona, Tucson, AZ.
Valentine N NfonsamDepartment of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ.
University of Arizona · US

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
NCI NIH HHS P30 CA023074PHS HHS
6 · The paper itself

Abstract

introductionThe aim of this study was to investigate and analyze the incidence of early-onset colorectal cancer in Arizona, using the Arizona Cancer Registry.

methodsWe performed a retrospective analysis of patients with colorectal cancer reported in the Arizona Cancer Registry from 1995-2010. Outcome measure: incidence of CRC in patients younger than 50 years.

results39,623 cases of colorectal cancer were reported to the Arizona Cancer Registry during a period of 15 years. Overall, there was a 17% decrease in the incidence of CRC. However, there was a 23% increase in incidence among patients in the age group 10-50. During the same time period, 15% and 41% increase in the incidence of colon and rectal cancer was observed, respectively. The most significant increase (102%) in overall CRC incidence was seen in the age group 10-29. The highest increase (110%) in incidence of colon cancer was observed in the same age group, while the most significant increase in incidence rates (225%) of rectal cancer was seen in the age group 30-34.

conclusionAlthough there is an overall decrease in incidence of colorectal cancer in Arizona, alarming increase in incidence of early-onset CRC was observed; mirroring the national trends.

Identifiers

PMID27559493
PMCPMC4993098
OpenAlexW2522427908

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.