Evidence map›Paper›PMID 27559467›Full record

ArticleClinical and translational allergy2016

Body mass index and physical activity in early childhood are associated with atopic sensitization, atopic dermatitis and asthma in later childhood.

Kristine Kjer Byberg, Geir Egil Eide, Michele R Forman, Pétur Benedikt Júlíusson, Knut Øymar

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In one paragraph

Article in Clinical and translational allergy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Prediction of allergic disease trajectories from birth up to adolescence.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
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  10. Paediatric asthma and non-allergic comorbidities: A review of current risk and proposed mechanisms.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022
    Review
  11. Self-Reported Physical Activity and Asthma Risk in Children.The journal of allergy and clinical immunology. In practice · 2022
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kristine Kjer BybergDepartment of Pediatrics, Stavanger University Hospital, POB 8100, 4068 Stavanger, Norway.ORCID 0000-0002-4529-2196
Geir Egil EideCentre for Clinical Research, Haukeland University Hospital, Bergen, Norway ; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Michele R FormanDepartment of Nutritional Sciences, School of Human Ecology, University of Texas at Austin, Austin, TX USA.
Pétur Benedikt JúlíussonDepartment of Pediatrics, Haukeland University Hospital, Bergen, Norway ; Department of Clinical Science, University of Bergen, Bergen, Norway.
Knut ØymarDepartment of Pediatrics, Stavanger University Hospital, POB 8100, 4068 Stavanger, Norway ; Department of Clinical Science, University of Bergen, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe results of studies on the associations of childhood excessive weight/obesity and physical activity with atopic sensitization and atopic diseases are inconsistent. We studied the associations of anthropometry and physical activity in childhood with atopic sensitization and atopic diseases in late childhood.

methodsIn a cohort study including cases exposed to preeclampsia during pregnancy and controls, anthropometry and physical activity were assessed at several ages in 617 children. Associations with atopic sensitization and atopic diseases in late childhood were analysed using multiple logistic regression.

resultsBody mass index standard deviation score (BMI SDS) at 1 year and low physical activity at 3-6 years were positively associated with atopic sensitization at 12.8 years [adjusted odds ratio (OR) 1.22; 95 % confidence interval (1.00, 1.49) and OR 2.36; (1.15, 4.81), respectively]. Change in BMI SDS from 1 to 4 years, BMI SDS at 4 years, and high physical activity at 6-10 years were positively associated with atopic dermatitis by 10.8 years [OR 1.46; (1.11, 1.92); OR 1.32; (1.06, 1.65) and OR 1.94; (1.16, 3.24); respectively]. Low physical activity at 3-6 and 6-10 years were positively associated with asthma by 10.8 years [OR 3.61; (1.56, 8.36) and OR 2.52; (1.24, 5.12), respectively].

conclusionsBMI and physical activity in early childhood were associated with atopic sensitization, atopic dermatitis and asthma in later childhood. Larger cohorts with repeated measurements of both predictors and outcomes are required to further elucidate this issue. Trial registration Our study was observational without any clinical intervention on the participants. Therefore, no trial registration number is available.

Indexed as

Allergic rhinitisAnthropometryAsthmaAtopic dermatitisChild

Identifiers

PMID27559467
PMCPMC4995660

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.