Evidence map›Paper›PMID 27559385›Full record

ArticleBeilstein journal of organic chemistry2016

Selective bromochlorination of a homoallylic alcohol for the total synthesis of (-)-anverene.

Frederick J Seidl, Noah Z Burns

Abstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. The Electrochemical cis-Chlorination of Alkenes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  4. Catalytic Regio- and Enantioselective Haloazidation of Allylic Alcohols.Journal of the American Chemical Society · 2018
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Frederick J SeidlDepartment of Chemistry, Stanford University, Stanford, California 94305, USA.
Noah Z BurnsDepartment of Chemistry, Stanford University, Stanford, California 94305, USA.

Funding

Selective Halogenation Reactions for the Synthesis of Chiral Bioactive Small MoleculesR01GM114061 · NIGMS · STANFORD UNIVERSITY · PI BURNS, NOAH ZACHARY · 2015 to 2019
$1.5M
NIGMS NIH HHS R01 GM114061
6 · The paper itself

Abstract

The scope of a recently reported method for the catalytic enantioselective bromochlorination of allylic alcohols is expanded to include a specific homoallylic alcohol. Critical factors for optimization of this reaction are highlighted. The utility of the product bromochloride is demonstrated by the first total synthesis of an antibacterial polyhalogenated monoterpene, (-)-anverene.

Indexed as

enantioselective catalysishalogenationnatural productstotal synthesis

Identifiers

PMID27559385
PMCPMC4979643

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.