Evidence map›Paper›PMID 27559025›Full record

ArticleThe Plant cell2016

A Family of Negative Regulators Targets the Committed Step of de Novo Fatty Acid Biosynthesis.

Matthew J Salie, Ning Zhang, Veronika Lancikova, Dong Xu, Jay J Thelen

Open access · greenAbstract read
In one paragraph

Article in The Plant cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Lipid regulation inFrontiers in plant science · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Evolution of the regulatory subunits for the heteromeric acetyl-CoA carboxylase.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Matthew J SalieDepartment of Biochemistry, University of Missouri-Columbia, Christopher S. Bond Life Sciences Center, Columbia, Missouri 65211.
Ning ZhangInformatics Institute and Department of Computer Science, University of Missouri-Columbia, Christopher S. Bond Life Sciences Center, Columbia, Missouri 65211.
Veronika LancikovaDepartment of Biochemistry, University of Missouri-Columbia, Christopher S. Bond Life Sciences Center, Columbia, Missouri 65211.ORCID http://orcid.org/0000-0002-9686-9645
Dong XuInformatics Institute and Department of Computer Science, University of Missouri-Columbia, Christopher S. Bond Life Sciences Center, Columbia, Missouri 65211.
Jay J ThelenDepartment of Biochemistry, University of Missouri-Columbia, Christopher S. Bond Life Sciences Center, Columbia, Missouri 65211 thelenj@missouri.edu.
University of Missouri · US

Funding

MOLECULAR BASIS OF GENE EXPRESSION AND SIGNAL PROCESSINGT32GM008396 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI HANNINK, MARK · 1991 to 2021
$4.1M
NIGMS NIH HHS T32 GM008396
6 · The paper itself

Abstract

Acetyl-CoA carboxylase (ACCase) catalyzes the committed step of de novo fatty acid biosynthesis. In prokaryotes, green algae, and most plants, this enzyme is a heteromeric complex requiring four different subunits for activity. The plant complex is recalcitrant to conventional purification schemes and hence the structure and composition of the full assembly have been unclear. In vivo coimmunoprecipitation using subunit-specific antibodies identified a novel family of proteins in

Identifiers

PMID27559025
PMCPMC5059801
OpenAlexW2512034269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.