Evidence map›Paper›PMID 27558850›Full record

ArticleJournal of the Royal Society, Interface2016

Bayesian uncertainty quantification for transmissibility of influenza, norovirus and Ebola using information geometry.

Thomas House, Ashley Ford, Shiwei Lan, Samuel Bilson, Elizabeth Buckingham-Jeffery, Mark Girolami

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thomas HouseSchool of Mathematics, University of Manchester, Oxford Road, Manchester M13 9PL, UK Warwick Infectious Disease Epidemiology Research Centre (WIDER), Warwick Mathematics Institute, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK thomas.house@manchester.ac.uk.ORCID 0000-0001-5835-8062
Ashley FordSchool of Mathematics, University of Bristol, Bristol BS8 1TW, UK.
Shiwei LanDepartment of Statistics, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Samuel BilsonWarwick Infectious Disease Epidemiology Research Centre (WIDER), Warwick Mathematics Institute, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Elizabeth Buckingham-JefferyWarwick Infectious Disease Epidemiology Research Centre (WIDER), Warwick Mathematics Institute, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK Complexity Science Doctoral Training Centre, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Mark GirolamiDepartment of Statistics, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious diseases exert a large and in many contexts growing burden on human health, but violate most of the assumptions of classical epidemiological statistics and hence require a mathematically sophisticated approach. Viral shedding data are collected during human studies-either where volunteers are infected with a disease or where existing cases are recruited-in which the levels of live virus produced over time are measured. These have traditionally been difficult to analyse due to strong, complex correlations between parameters. Here, we show how a Bayesian approach to the inverse problem together with modern Markov chain Monte Carlo algorithms based on information geometry can overcome these difficulties and yield insights into the disease dynamics of two of the most prevalent human pathogens-influenza and norovirus-as well as Ebola virus disease.

Indexed as

Caliciviridae InfectionsEbolavirusHemorrhagic Fever, EbolaInfluenza A virusInfluenza, HumanModels, BiologicalNorovirusBayes TheoremHumanscompartmental modelMarkov chain Monte Carloshedding

Identifiers

PMID27558850
PMCPMC5014059

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.