ArticleScientific reports2016
Polycomb-group protein SlMSI1 represses the expression of fruit-ripening genes to prolong shelf life in tomato.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 40 citations in OpenAlex.
- Dynamic regulatory mechanisms of histone methylation in plant development and environmental adaptation.Horticulture research · 2026Article
- Epigenetics in the modern era of crop improvements.Science China. Life sciences · 2025Review
- Review
- Identification of grape H3K27 methyltransferase genes and their expression profiles during grape fruit ripening.Molecular biology reports · 2024Article
- Current insights into posttranscriptional regulation of fleshy fruit ripening.Plant physiology · 2023Review
- Histone H3K4 methyltransferase DcATX1 promotes ethylene induced petal senescence in carnation.Plant physiology · 2023Article
- Epigenetic regulation in tomato fruit ripening.Frontiers in plant science · 2023Review
- Exploitation of epigenetic variation of crop wild relatives for crop improvement and agrobiodiversity preservation.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Review
- Molecular and biochemical basis of softening in tomato.Molecular horticulture · 2022Review
- Perspectives for epigenetic editing in crops.Transgenic research · 2021Review
- Genome-Wide Identification and Analysis of the Polycomb Group Family inInternational journal of molecular sciences · 2021Article
- Overexpression of SlMYB75 enhances resistance to Botrytis cinerea and prolongs fruit storage life in tomato.Plant cell reports · 2021Article
- Structural and Functional Diversification of SEPALLATA Genes TM5 and RIN in Tomato Species (Section Lycopersicon).Doklady. Biochemistry and biophysics · 2020Article
- PcG Proteins MSI1 and BMI1 Function Upstream of miR156 to Regulate Aerial Tuber Formation in Potato.Plant physiology · 2020Article
- Rosaceae Fruit Development, Ripening and Post-harvest: An Epigenetic Perspective.Frontiers in plant science · 2017Review
- Evaluation of multiple approaches to identify genome-wide polymorphisms in closely related genotypes of sweet cherry (Computational and structural biotechnology journal · 2017Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polycomb-group (PcG) protein MULTICOPY SUPPRESSOR OF IRA1 (MSI1) protein is an evolutionarily conserved developmental suppressor and plays a crucial role in regulating epigenetic modulations. However, the potential role and function of MSI1 in fleshy fruits remain unknown. In this study, SlMSI1 was cloned and transformed into tomato to explore its function. The quantitative real-time PCR results showed that SlMSI1 was highly expressed in flowers and fruits and that its transcript and protein levels were significantly decreased in fruits after the breaker stage. Additionally, SlMSI1-overexpressing transgenic tomatoes displayed abnormal non-ripening fruit formation, whereas its suppression promoted fruit ripening in transgenic tomatoes. Quantitative real-time PCR assays also showed that RIN and its regulons were decreased in SlMSI1 overexpression transgenic tomato fruits. Furthermore, RNA-seq analysis demonstrated that SlMSI1 inhibits fruit ripening by negatively regulating a large set of fruit-ripening genes in addition to RIN and its regulons. Finally, genetic manipulation of SlMSI1 and RIN successfully prolonged the fruit shelf life by regulating the fruit-ripening genes in tomato. Our findings reveal a novel regulatory function of SlMSI1 in fruit ripening and provide a new regulator that may be useful for genetic engineering and modification of fruit shelf life.
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