Evidence map›Paper›PMID 27558480›Full record

ReviewCurrent genetics2017

A conserved role of the RSC chromatin remodeler in the establishment of nucleosome-depleted regions.

Carlo Yague-Sanz, Enrique Vázquez, Mar Sánchez, Francisco Antequera, Damien Hermand

Abstract readReview
In one paragraph

Review in Current genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  3. Cryo-EM structures reveal the acetylation process of piccolo NuA4.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carlo Yague-SanzURPHYM-GEMO, Namur Research College (NARC), The University of Namur, 5000, Namur, Belgium.
Enrique VázquezInstituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC)/Universidad de Salamanca, Campus Miguel de Unamuno, 37007, Salamanca, Spain.
Mar SánchezInstituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC)/Universidad de Salamanca, Campus Miguel de Unamuno, 37007, Salamanca, Spain.
Francisco AntequeraInstituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC)/Universidad de Salamanca, Campus Miguel de Unamuno, 37007, Salamanca, Spain.
Damien HermandURPHYM-GEMO, Namur Research College (NARC), The University of Namur, 5000, Namur, Belgium. Damien.Hermand@unamur.be.ORCID http://orcid.org/0000-0002-1029-5848

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The occupancy of nucleosomes governs access to the eukaryotic genomes and results from a combination of biophysical features and the effect of ATP-dependent remodelling complexes. Most promoter regions show a conserved pattern characterized by a nucleosome-depleted region (NDR) flanked by nucleosomal arrays. The conserved RSC remodeler was reported to be critical to establish NDR in vivo in budding yeast but other evidences suggested that this activity may not be conserved in fission yeast. By reanalysing and expanding previously published data, we propose that NDR formation requires, at least partially, RSC in both yeast species. We also discuss the most prominent biological role of RSC and the possibility that non-essential subunits do not define alternate versions of the complex.

Indexed as

Adenosine TriphosphatasesChromatin Assembly and DisassemblyGene Expression ProfilingGene Expression Regulation, FungalNucleosomesSaccharomyces cerevisiae ProteinsSaccharomycetalesSchizosaccharomycesSchizosaccharomyces pombe ProteinsSpecies SpecificityAdenosine TriphosphatasesNucleosomesSaccharomyces cerevisiae ProteinsSchizosaccharomyces pombe ProteinsChromatinMitosisNucleosomeRSCYeast

Identifiers

PMID27558480
PMCPMC5383693

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.