ArticleScientific reports2016
Biofilm may not be Necessary for the Epidemic Spread of Acinetobacter baumannii.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The trial behind it
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Who cites it
18 citing papers in PubMed.
- Assessing the public health risk from ESKAPE pathogens including MRSA and VRE on high-touch shopping cart surfaces.AIMS public health · 2026Review
- Whole-genome sequencing and characterization ofFrontiers in microbiology · 2026Article
- Biofilm Formation in ClinicalBioMed research international · 2026Article
- Relationship between antibiotic resistance and biofilm-forming capacity with RND efflux pumps expression in clinical Acinetobacter baumannii isolates.Archives of microbiology · 2025Article
- Article
- Heterogeneity and Genomic Plasticity of Acinetobacter baumannii and Acinetobacter nosocomialis Isolates Recovered from Clinical Samples in India.Current microbiology · 2024Article
- Exploring the evolutionary and pathogenic role of Acinetobacter baumannii biofilm-associated protein (Bap) through in silico structural modeling.Archives of microbiology · 2024Article
- Review
- Gram-Negative Bacteria Holding Together in a Biofilm: TheMicroorganisms · 2021Review
- Antibiotic Resistance and Genotypes of Nosocomial Strains ofAntibiotics (Basel, Switzerland) · 2021Article
- Molecular characterization and antibiotic resistance of Acinetobacter baumannii in cerebrospinal fluid and blood.PloS one · 2021Article
- AntimicrobialMolecules (Basel, Switzerland) · 2020Article
- Article
- Carbapenem-ResistantFrontiers in microbiology · 2019Article
- Review
- Article
- Surface-Related Features and Virulence AmongFrontiers in microbiology · 2018Article
- Biofilm is a Major Virulence Determinant in Bacterial Colonization of Chronic Skin Ulcers Independently from the Multidrug Resistant Phenotype.International journal of molecular sciences · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilm is recognized as a contributing factor to the capacity of Acinetobacter baumannii to persist and prosper in medical settings, but it is still unknown whether biofilms contribute to the spread of A. baumannii. In this study, the biofilm formation of 114 clinical A. baumannii isolates and 32 non-baumannii Acinetobacter isolates was investigated using a microtiter plate assay. The clonal relationships among A. baumannii isolates were assessed using pulsed-field gel electrophoresis and multilocus sequence typing, and one major outbreak clone and 5 other epidemic clones were identified. Compared with the epidemic or outbreak A. baumannii isolates, the sporadic isolates had significantly higher biofilm formation, but no significant difference was observed between the sporadic A. baumannii isolates and the non-baumannii Acinetobacter isolates, suggesting that biofilm is not important for the epidemic spread of A. baumannii. Of the multidrug-resistant (MDR) A. baumannii isolates in this study, 95.7% were assigned to international clone 2 (IC2) and showed significantly lower biofilm formations than the other isolates, suggesting that biofilm did not contribute to the high success of IC2. These findings have increased our understanding of the potential relationship between biofilm formation and the epidemic capacity of A. baumannii.
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