Evidence map›Paper›PMID 27557995›Full record

ArticlePharmacoEconomics2017

Mapping Between the Sydney Asthma Quality of Life Questionnaire (AQLQ-S) and Five Multi-Attribute Utility Instruments (MAUIs).

Billingsley Kaambwa, Gang Chen, Julie Ratcliffe, Angelo Iezzi, Aimee Maxwell, Jeff Richardson

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in PharmacoEconomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Do country-specific preference weights matter in the choice of mapping algorithms? The case of mapping the Diabetes-39 onto eight country-specific EQ-5D-5L value sets.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Pooled it
  3. Pooled it
  4. Predicting EuroQol (EQ-5D-5 L) health state utilities from functional outcomes of sleep questionnaire (FOSQ-10) scores.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
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  6. Mapping the 12-item World Health Organization disability assessment schedule 2.0 (WHODAS 2.0) onto the assessment of quality of life (AQoL)-4D utilities.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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  11. Living Well with Pollution? The Impact of the Concentration of PMInternational journal of environmental research and public health · 2019
    Article
  12. Testing alternative regression models to predict utilities: mapping the QLQ-C30 onto the EQ-5D-5L and the SF-6D.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
  13. Development of Methods for the Mapping of Utilities Using Mixture Models: Mapping the AQLQ-S to the EQ-5D-5L and the HUI3 in Patients with Asthma.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2018
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Billingsley KaambwaFlinders Health Economics Group, Flinders University, A Block, Repatriation General Hospital, 202-16 Daws Road, Daw Park, Adelaide, SA, 5041, Australia. billingsley.kaambwa@flinders.edu.au.
Gang ChenCentre for Health Economics, Building 75, 15 Innovation Walk, Monash University, Clayton, VIC, 3800, Australia.
Julie RatcliffeFlinders Health Economics Group, Flinders University, A Block, Repatriation General Hospital, 202-16 Daws Road, Daw Park, Adelaide, SA, 5041, Australia.
Angelo IezziCentre for Health Economics, Building 75, 15 Innovation Walk, Monash University, Clayton, VIC, 3800, Australia.
Aimee MaxwellCentre for Health Economics, Building 75, 15 Innovation Walk, Monash University, Clayton, VIC, 3800, Australia.
Jeff RichardsonCentre for Health Economics, Building 75, 15 Innovation Walk, Monash University, Clayton, VIC, 3800, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEconomic evaluation of health services commonly requires information regarding health-state utilities. Sometimes this information is not available but non-utility measures of quality of life may have been collected from which the required utilities can be estimated. This paper examines the possibility of mapping a non-utility-based outcome, the Sydney Asthma Quality of Life Questionnaire (AQLQ-S), onto five multi-attribute utility instruments: Assessment of Quality of Life 8 Dimensions (AQoL-8D), EuroQoL 5 Dimensions 5-Level (EQ-5D-5L), Health Utilities Index Mark 3 (HUI3), 15 Dimensions (15D), and the Short-Form 6 Dimensions (SF-6D).

methodsData for 856 individuals with asthma were obtained from a large Multi-Instrument Comparison (MIC) survey. Four statistical techniques were employed to estimate utilities from the AQLQ-S. The predictive accuracy of 180 regression models was assessed using six criteria: mean absolute error (MAE), root mean squared error (RMSE), correlation, distribution of predicted utilities, distribution of residuals, and proportion of predictions with absolute errors <0.0.5. Validation of initial 'primary' models was carried out on a random sample of the MIC data.

resultsBest results were obtained with non-linear models that included a quadratic term for the AQLQ-S score along with demographic variables. The four statistical techniques predicted models that performed differently when assessed by the six criteria; however, the best results, for both the estimation and validation samples, were obtained using a generalised linear model (GLM estimator).

conclusionsIt is possible to predict valid utilities from the AQLQ-S using regression methods. We recommend GLM models for this exercise.

Indexed as

Models, StatisticalQuality of LifeSurveys and QuestionnairesAdolescentAdultAgedAsthmaFemaleHealth StatusHumansLinear ModelsMaleMiddle AgedNonlinear DynamicsRegression AnalysisYoung Adult

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.