Evidence map›Paper›PMID 27557946›Full record

ArticleBlood2016

Regulation of Vegf signaling by natural and synthetic ligands.

Andrea Rossi, Sebastien Gauvrit, Michele Marass, Luyuan Pan, Cecilia B Moens, Didier Y R Stainier

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Blood, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 70 citations in OpenAlex.

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  17. Modulation of VEGFA Signaling During Heart Regeneration in Zebrafish.Methods in molecular biology (Clifton, N.J.) · 2022
    Review
  18. Article
  19. Article
  20. Genetics in Light of Transcriptional Adaptation.Trends in genetics : TIG · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Andrea RossiDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.ORCID 0000-0001-5863-6448
Sebastien GauvritDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
Michele MarassDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
Luyuan PanDivision of Basic Science, Fred Hutchinson Cancer Research Center, Seattle, WA; and.
Cecilia B MoensDivision of Basic Science, Fred Hutchinson Cancer Research Center, Seattle, WA; and.
Didier Y R StainierDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
Max Planck Institute for Heart and Lung Research · DEChinese Academy of Sciences · CNFred Hutch Cancer Center · US

Funding

Mechanisms of Tangential Neuron MigrationR01NS082567 · NINDS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MOENS, CECILIA B · 2013 to 2017
$2.1M
TILLING the Zebrafish Genome: A Reverse Genetics ApproachR01HD076585 · NICHD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MOENS, CECILIA B, SOLNICAKREZEL, LILIANNA · 2012 to 2014
$1.9M
NICHD NIH HHS R01 HD076585NINDS NIH HHS R01 NS082567
6 · The paper itself

Abstract

The mechanisms that allow cells to bypass anti-vascular endothelial growth factor A (VEGFA) therapy remain poorly understood. Here we use zebrafish to investigate this question and first show that

Indexed as

Signal TransductionAgingAnimalsArteriesCell DifferentiationGenes, DominantLigandsMutationNeovascularization, PhysiologicProtein EngineeringRNA, MessengerVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-1ZebrafishZebrafish ProteinsLigandsRNA, MessengerVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-1Zebrafish Proteins

Identifiers

PMID27557946
PMCPMC5766839
OpenAlexW2510762900

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.