ReviewClinical research in cardiology : official journal of the German Cardiac Society2017
Electronic health records to facilitate clinical research.
Review in Clinical research in cardiology : official journal of the German Cardiac Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 300 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
300 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Efficacy of antiobesity medications for weight reduction in older adults: a systematic review.Obesity (Silver Spring, Md.) · 2025Pooled it
- Methodological challenges using routine clinical care data for real-world evidence: a rapid review utilizing a systematic literature search and focus group discussion.BMC medical research methodology · 2025Pooled it
- The validity of electronic health data for measuring smoking status: a systematic review and meta-analysis.BMC medical informatics and decision making · 2024Pooled it
- Comprehensive review of Korean Medicine registries 2015-2023.Frontiers in medicine · 2024Pooled it
- Transforming epilepsy research: A systematic review on natural language processing applications.Epilepsia · 2023Pooled it
- Electronic health records in Brazil: Prospects and technological challenges.Frontiers in public health · 2022Pooled it
- Use of comprehensive recruitment strategies in the glycemia reduction approaches in diabetes: A comparative effectiveness study (GRADE) multi-center clinical trial.Clinical trials (London, England) · 2023 · on this mapTrial
- A Centralized EHR-Based Model for the Recruitment of Rural and Lower Socioeconomic Participants in Pragmatic Trials: A Secondary Analysis of the Diuretic Comparison Project.JAMA network open · 2023Trial
- Trial
- Association of CBC‑derived inflammation indices with prevalent CKD: a cross‑sectional analysis of a Chinese data set and NHANES.Annals of medicine · 2026Article
- Augmenting structured diagnoses through effective use of pre-trained large language models on clinical notes.JAMIA open · 2026Article
- Prevalence and penetrance of heritable retinoblastoma in two adult population cohorts: implications for genomic newborn screening.European journal of human genetics : EJHG · 2026Article
- Real-World Actionability Analysis of Comprehensive Genomic Profiling Versus Single/Small-Gene Panels.Oncology and therapy · 2026Article
- Leveraging Data Science for Conducting Observational Studies: Highlighting Advantages and Limitations Throughout the Evaluation of a Use Case.Mayo Clinic proceedings. Digital health · 2026Article
- Lung cancer research: how natural language processing enhances clinical data extraction.Journal of thoracic disease · 2026Article
- Recombinant shingles vaccination and the risk of cardiovascular events.Nature medicine · 2026Article
- Exploring patient motivations and preferences for medical data sharing with researchers: a simulation study using the iAgree platform.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- Data resource profile: Australian and New Zealand Hip Fracture Registry (ANZHFR).Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2026Article
- Generalizable multilingual medical text anonymization using generative instruction tuning.Communications medicine · 2026Article
- Automatic identification of diagnosis from hospital discharge letters via weakly supervised Natural Language Processing.Scientific reports · 2026Article
240 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
Abstract
Electronic health records (EHRs) provide opportunities to enhance patient care, embed performance measures in clinical practice, and facilitate clinical research. Concerns have been raised about the increasing recruitment challenges in trials, burdensome and obtrusive data collection, and uncertain generalizability of the results. Leveraging electronic health records to counterbalance these trends is an area of intense interest. The initial applications of electronic health records, as the primary data source is envisioned for observational studies, embedded pragmatic or post-marketing registry-based randomized studies, or comparative effectiveness studies. Advancing this approach to randomized clinical trials, electronic health records may potentially be used to assess study feasibility, to facilitate patient recruitment, and streamline data collection at baseline and follow-up. Ensuring data security and privacy, overcoming the challenges associated with linking diverse systems and maintaining infrastructure for repeat use of high quality data, are some of the challenges associated with using electronic health records in clinical research. Collaboration between academia, industry, regulatory bodies, policy makers, patients, and electronic health record vendors is critical for the greater use of electronic health records in clinical research. This manuscript identifies the key steps required to advance the role of electronic health records in cardiovascular clinical research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.