ArticleNeuroImage2017
Phase-amplitude coupling at the organism level: The amplitude of spontaneous alpha rhythm fluctuations varies with the phase of the infra-slow gastric basal rhythm.
Article in NeuroImage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.
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Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Coactivation of Autonomic and Central Nervous Systems During Processing of Socially Relevant Information in Autism Spectrum Disorder: A Systematic Review.Neuropsychology review · 2024Pooled it
- Controlled deep breathing technique intervention effects on resting EEG, subjective psychological distress, and executive function performance in young adults.Frontiers in public health · 2026Trial
- The Impact of Alpha-Neurofeedback Training on Gastric Slow Wave Activity and Heart Rate Variability in Humans.Neurogastroenterology and motility · 2025Trial
- The Mind From Within: Visceral Roots of Human Cognition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Potential mechanisms and functional significance of aperiodic neural activity.Nature human behaviour · 2026Review
- The priming effect of interoception on savoring positive emotion: An EEG study.Cognitive, affective & behavioral neuroscience · 2026Article
- Dynamic Respiration-Neural Coupling in Substantia Nigra across Sleep and Anesthesia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Beyond representations: from active inference to active interference.Frontiers in human neuroscience · 2026Article
- Attentional modulation of multisensory integration across the cortical hierarchy.Frontiers in neural circuits · 2026Review
- I sync, therefore I am: brain-body synchrony in typical and disordered consciousness.Neuroscience of consciousness · 2026Review
- Time, space, memory and brain-body rhythms.Nature reviews. Neuroscience · 2026Review
- Cardiac, respiratory, and gastric rhythms independently modulate motor corticospinal excitability in humans.PLoS biology · 2025Article
- The gut feeling in motion sickness.Communications biology · 2025Review
- It Is Movement All the Way Down: Broken Rhythms and Embodied Selfhood in Depersonalization.Behavioral sciences (Basel, Switzerland) · 2025Article
- Increased Modulation of Low-Frequency Cardiac Rhythms on Resting-State Left Insula Alpha Oscillations in Major Depressive Disorder: Evidence from a Magnetoencephalography Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Brain-body dysconnectivity: deficient autonomic regulation of cortical function in first-episode schizophrenia.Psychological medicine · 2025Article
- Transcranial 1064-nm laser photobiomodulation modulates frequency-specific cortical source dynamics and functional connectivity in healthy adults.Frontiers in human neuroscience · 2025Article
- Dissociative Symptoms and Interoceptive Integration.Current topics in behavioral neurosciences · 2025Review
- Brain-body interactions associated with the transition from mind wandering to awareness of its occurrence.Neuroscience of consciousness · 2025Article
- The effect of cardiac phase on distractor suppression and motor inhibition in a stop-signal task.Scientific reports · 2024Article
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Abstract
A fundamental feature of the temporal organization of neural activity is phase-amplitude coupling between brain rhythms at different frequencies, where the amplitude of a higher frequency varies according to the phase of a lower frequency. Here, we show that this rule extends to brain-organ interactions. We measured both the infra-slow (~0.05Hz) rhythm intrinsically generated by the stomach - the gastric basal rhythm - using electrogastrography, and spontaneous brain dynamics with magnetoencephalography during resting-state with eyes open. We found significant phase-amplitude coupling between the infra-slow gastric phase and the amplitude of the cortical alpha rhythm (10-11Hz), with gastric phase accounting for 8% of the variance of alpha rhythm amplitude fluctuations. Gastric-alpha coupling was localized to the right anterior insula, and bilaterally to occipito-parietal regions. Transfer entropy, a measure of directionality of information transfer, indicates that gastric-alpha coupling is due to an ascending influence from the stomach to both the right anterior insula and occipito-parietal regions. Our results show that phase-amplitude coupling so far only observed within the brain extends to brain-viscera interactions. They further reveal that the temporal structure of spontaneous brain activity depends not only on neuron and network properties endogenous to the brain, but also on the slow electrical rhythm generated by the stomach.
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