ArticleLangmuir : the ACS journal of surfaces and colloids2016
A Fibrous Localized Drug Delivery Platform with NIR-Triggered and Optically Monitored Drug Release.
Article in Langmuir : the ACS journal of surfaces and colloids, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Advances in Light-Responsive Smart Multifunctional Nanofibers: Implications for Targeted Drug Delivery and Cancer Therapy.Pharmaceutics · 2024Review
- Phototriggered structures: Latest advances in biomedical applications.Acta pharmaceutica Sinica. B · 2023Review
- Breast cancer brain metastasis: from etiology to state-of-the-art modeling.Journal of biological engineering · 2023Review
- On-Demand Drug Delivery Systems Using Nanofibers.Nanomaterials (Basel, Switzerland) · 2021Review
- Biotechnological Applications of Polymeric Nanofiber Platforms Loaded with Diverse Bioactive Materials.Polymers · 2021Review
- Stimuli-Responsive Nanofibers Containing Gold Nanorods for On-Demand Drug Delivery Platforms.Pharmaceutics · 2021Article
- Recent advances in innovative strategies for enhanced cancer photodynamic therapy.Theranostics · 2021Review
- 3D printed intelligent scaffold prevents recurrence and distal metastasis of breast cancer.Theranostics · 2020Article
- Poly(ε-caprolactone) (PCL) Hollow Nanoparticles with Surface Sealability and On-Demand Pore Generability for Easy Loading and NIR Light-Triggered Release of Drug.Pharmaceutics · 2019Article
- Enhancement of Photodynamic Cancer Therapy by Physical and Chemical Factors.Angewandte Chemie (International ed. in English) · 2019Review
- Gold Nanocage-Incorporated Poly(ε-Caprolactone) (PCL) Fibers for Chemophotothermal Synergistic Cancer Therapy.Pharmaceutics · 2019Article
- Nanomaterials as photothermal therapeutic agents.Progress in materials science · 2019Article
- Multifunctional Electrospun Nanofibers for Enhancing Localized Cancer Treatment.Small (Weinheim an der Bergstrasse, Germany) · 2018Review
- Preparation of Stable Silver Nanoparticles Having Wide Red-To-Near-Infrared Extinction.Global challenges (Hoboken, NJ) · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Implantable localized drug delivery systems (LDDSs) with intelligent functionalities have emerged as a powerful chemotherapeutic platform in curing cancer. Developing LDDSs with rationally controlled drug release and real-time monitoring functionalities holds promise for personalized therapeutic protocols but suffers daunting challenges. To overcome such challenges, a series of porous Yb(3+)/Er(3+) codoped CaTiO3 (CTO:Yb,Er) nanofibers, with specifically designed surface functionalization, were synthesized for doxorubicin (DOX) delivery. The content of DOX released could be optically monitored by increase in the intensity ratio of green to red emission (I550/I660) of upconversion photoluminescent nanofibers under 980 nm near-infrared (NIR) excitation owing to the fluorescence resonance energy transfer (FRET) effect between DOX molecules and the nanofibers. More importantly, the 808 nm NIR irradiation enabled markedly accelerated DOX release, confirming representative NIR-triggered drug release properties. In consequence, such CTO:Yb,Er nanofibers presented significantly enhanced in vitro anticancer efficacy under NIR irradiation. This study has thus inspired another promising fibrous LDDS platform with NIR-triggered and optics-monitored DOX releasing for personalized tumor chemotherapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.