Evidence map›Paper›PMID 27556952›Full record

ReviewBiochimica et biophysica acta. Molecular and cell biology of lipids2017

Biosynthesis, remodeling and turnover of mitochondrial cardiolipin.

Michael Schlame, Miriam L Greenberg

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta. Molecular and cell biology of lipids, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

140 citing papers in PubMed.

  1. Virulence · 2026
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  15. Insect Lipidomics: Advances, Applications, and Physiological Insights.Advances in experimental medicine and biology · 2026
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review

80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael SchlameDepartment of Anesthesiology and Cell Biology, New York University School of Medicine, New York, NY 10016, USA. Electronic address: michael.schlame@med.nyu.edu.
Miriam L GreenbergDepartment of Biological Sciences, Wayne State University, Detroit, MI 48202, USA.

Funding

THE ROLE OF CARDIOLIPIN IN THE TCA CYCLE: IMPLICATIONS FOR BARTH SYNDROMER01HL117880 · NHLBI · WAYNE STATE UNIVERSITY · PI GREENBERG, MIRIAM L · 2014 to 2023
$3.0M
Aberrant Cardiolipin Dynamics in Barth Syndrome - Renewal - 1R01GM115593 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SCHLAME, MICHAEL · 2015 to 2023
$2.9M
NHLBI NIH HHS R01 HL117880NIGMS NIH HHS R01 GM115593
6 · The paper itself

Abstract

Among mitochondrial lipids, cardiolipin occupies a unique place. It is the only phospholipid that is specific to mitochondria and although it is merely a minor component, accounting for 10-20% of the total phospholipid content, cardiolipin plays an important role in the molecular organization, and thus the function of the cristae. This review covers the formation of cardiolipin, a phospholipid dimer containing two phosphatidyl residues, and its assembly into mitochondrial membranes. While a large body of literature exists on this topic, the review focuses on papers that appeared in the past three years. This article is part of a Special Issue entitled: Lipids of Mitochondria edited by Guenther Daum.

Indexed as

AnimalsCardiolipinsHumansMitochondriaMitochondrial MembranesPhospholipidsProtein BiosynthesisCardiolipinsPhospholipidsLipidsMembrane assemblyMetabolismMitochondria

Identifiers

PMID27556952
PMCPMC5125896

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.