Evidence map›Paper›PMID 27556081›Full record

ArticleEndoscopy international open2016

Efficacy and safety of endoscopic mucosal resection of non-ampullary duodenal polyps: a systematic review.

Udayakumar Navaneethan, Muhammad K Hasan, Vennisvasanth Lourdusamy, Xiang Zhu, Robert H Hawes, Shyam Varadarajulu

Abstract read
In one paragraph

Article in Endoscopy international open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Cryoballoon treatment of endoscopically unresectable duodenal adenomas.World journal of gastrointestinal endoscopy · 2026
    Article
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  14. Review
  15. Efficacy, feasibility, and safety of endoscopic double closure in the GI tract.iGIE : innovation, investigation and insights · 2022
    Article
  16. Article
  17. Article
  18. Endoscopic Treatment for Superficial Nonampullary Duodenal Tumors.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2021
    Review
  19. Article
  20. Endoscopic mucosal resectionWorld journal of gastrointestinal oncology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Udayakumar NavaneethanCenter for Interventional Endoscopy, Orlando, FL, USA.
Muhammad K HasanCenter for Interventional Endoscopy, Orlando, FL, USA.
Vennisvasanth LourdusamyCenter for Interventional Endoscopy, Orlando, FL, USA; Department of Internal Medicine, Brandon Regional Hospital, Brandon, FL, USA.
Xiang ZhuCenter for Interventional Endoscopy, Orlando, FL, USA.
Robert H HawesCenter for Interventional Endoscopy, Orlando, FL, USA.
Shyam VaradarajuluCenter for Interventional Endoscopy, Orlando, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsData on the safety and efficacy of endoscopic resection of non-ampullary duodenal polyps are limited. This study evaluated the safety and efficacy of endoscopic mucosal resection (EMR) of sporadic non-ampullary duodenal polyps.

methodsRelevant studies for the meta-analysis were identified through search of PUBMED and EMBASE databases. Studies employing EMR for the management of sporadic duodenal polyps in the non-ampullary region were included. The primary outcome was the surgical intervention rates due to non-curative endoscopic resection (incomplete removal/recurrence necessitating surgery) and/or management of procedural adverse events.

resultsA total of 440 patients (485 duodenal polyps) from 14 studies were included. The mean size of the polyps was 13 mm to 35 mm. Surgical intervention due to non-curative EMR and adverse events was required in 2 % (95 % confidence interval [CI] 0 - 4 %). EMR was successfully accomplished in 93 % (95 %CI 89 - 97 %). The overall bleeding rate after EMR was 16 % (95 %CI 10 - 23 %), and the pooled delayed bleeding rate was 5 % (95 %CI 2 - 7 %). The overall incidence of perforation was 1 % (95 %CI 1 - 3 %). Over a median follow-up period of 6 - 72 months, the recurrence rate after EMR was 15 % (95 %CI 7 - 23 %). Six studies (pooled recurrence 20 %, 95 %CI 14 - 27 %) reported on the outcomes of managing recurrent polyps, for which endoscopic removal was successful in 62 % (95 %CI 37 - 87 %). There was no procedure related mortality.

conclusionEMR appears to be a safe and effective therapeutic option for management of sporadic non-ampullary duodenal polyps. Long-term endoscopic surveillance is required to manage and treat recurrent disease.

Identifiers

PMID27556081
PMCPMC4993908

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.