ArticleFrontiers in microbiology2016
Production of Thermostable Organic Solvent Tolerant Keratinolytic Protease from Thermoactinomyces sp. RM4: IAA Production and Plant Growth Promotion.
Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Production, biochemical characterization, and kinetic/thermodynamic analysis of a novel keratinase from Bacillus sp. MSGU2024.Biotechnology letters · 2026Article
- Keratinolytic proteases secreted by Bacillus subtilis obtained from feather-based submerged culture.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Airborne Bacterial Communities: Diversity, Survival Strategies and Functional Roles in the Atmosphere.Environmental microbiology reports · 2026Review
- Functional identification of a feather-degrading thermitase-like S8 serine protease fromFrontiers in microbiology · 2026Article
- Current Understanding of Feather Keratin and Keratinase and Their Applications in Biotechnology.Biochemistry research international · 2025Review
- Hydrophobic aerogel-modified hemostatic gauze with thermal management performance.Bioactive materials · 2023Article
- The degradation of chicken feathers by3 Biotech · 2023Article
- Enhanced keratinase production by3 Biotech · 2022Article
- Isolation and identification of a feather degrading Bacillus tropicus strain Gxun-17 from marine environment and its enzyme characteristics.BMC biotechnology · 2022Article
- Chicken Feather Waste Valorization Into Nutritive Protein Hydrolysate: Role of Novel Thermostable Keratinase FromFrontiers in microbiology · 2022Article
- Chicken Feather Waste Hydrolysate as a Superior Biofertilizer in Agroindustry.Current microbiology · 2021Review
- Industrial sustainability of microbial keratinases: production and potential applications.World journal of microbiology & biotechnology · 2021Review
- Microbial keratinase and the bio-economy: a three-decade meta-analysis of research exploit.AMB Express · 2021Article
- Bacillus sp. CSK2 produced thermostable alkaline keratinase using agro-wastes: keratinolytic enzyme characterization.BMC biotechnology · 2020Article
- Enzyme Bioprospection of Marine-Derived Actinobacteria from the Chilean Coast and New Insight in the Mechanism of Keratin Degradation inMarine drugs · 2020Article
- Citrobacter diversus-derived keratinases and their potential application as detergent-compatible cloth-cleaning agents.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- Article
- Microbial Keratinase: Next Generation Green Catalyst and Prospective Applications.Frontiers in microbiology · 2020Review
- Extracellular Production, Characterization, and Engineering of a Polyextremotolerant Subtilisin-Like Protease From Feather-DegradingFrontiers in microbiology · 2020Article
- Cloning and expression of a thermostable keratinase gene from Thermoactinomyces sp. YT06 in Escherichia coli and characterization of purified recombinant enzymes.World journal of microbiology & biotechnology · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are several reports about the optimization of protease production, but only few have optimized the production of organic solvent tolerant keratinolytic proteases that show remarkable exploitation in the development of the non-polluting processes in biotechnological industries. The present study was carried with aim to optimize the production of a thermostable organic solvent tolerant keratinolytic protease Thermoactinomyces sp. RM4 utilizing chicken feathers. Thermoactinomyces sp. RM4 isolated from the soil sample collected from a rice mill wasteyard site near Kashipur, Uttrakhand was identified on the basis of 16S rDNA analysis. The production of organic solvent tolerant keratinolytic protease enzyme by Thermoactinomyces sp. RM4 was optimized by varying physical culture conditions such as pH (10.0), temperature (60°C), inoculum percentage (2%), feather concentration (2%) and agitation rate (2 g) for feather degradation. The result showed that Thermoactinomyces sp. RM4 potentially produces extra-cellular thermostable organic solvent tolerant keratinolytic protease in the culture medium. Further, the feather hydrolysate from keratinase production media showed plant growth promoting activity by producing indole-3-acetic acid itself. The present findings suggest that keratinolytic protease from Thermoactinomyces sp. RM4 offers enormous industrial applications due to its organic solvent tolerant property in peptide synthesis, practical role in feather degradation and potential function in plant growth promoting activity, which might be a superior candidate to keep ecosystem healthy and functional.
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