Evidence map›Paper›PMID 27555657›Full record

ReviewRadiation protection dosimetry2016

Evolution and Optimization of Tooth Models for Testing In Vivo EPR Tooth Dosimetry.

Kyo Kobayashi, Ruhong Dong, Roberto Javier Nicolalde, Benjamin B Williams, Gaixin Du, Harold M Swartz, Ann Barry Flood

Abstract readEvaluation StudyReview
In one paragraph

Review in Radiation protection dosimetry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kyo KobayashiEPR Center for the Study of Viable Systems, Radiology Department, Geisel School of Medicine at Dartmouth, HB 7785, Williamson Translational Research Bldg. Lebanon, NH, USA.
Ruhong DongEPR Center for the Study of Viable Systems, Radiology Department, Geisel School of Medicine at Dartmouth, HB 7785, Williamson Translational Research Bldg. Lebanon, NH, USA.
Roberto Javier NicolaldeNicolalde R&D, LLC, West Lebanon, NH, USA.
Benjamin B WilliamsEPR Center for the Study of Viable Systems, Radiology Department, Geisel School of Medicine at Dartmouth, HB 7785, Williamson Translational Research Bldg. Lebanon, NH, USA.
Gaixin DuEPR Center for the Study of Viable Systems, Radiology Department, Geisel School of Medicine at Dartmouth, HB 7785, Williamson Translational Research Bldg. Lebanon, NH, USA.
Harold M SwartzEPR Center for the Study of Viable Systems, Radiology Department, Geisel School of Medicine at Dartmouth, HB 7785, Williamson Translational Research Bldg. Lebanon, NH, USA.
Ann Barry FloodEPR Center for the Study of Viable Systems, Radiology Department, Geisel School of Medicine at Dartmouth, HB 7785, Williamson Translational Research Bldg. Lebanon, NH, USA Ann.B.Flood@Dartmouth.edu.

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
Scientific and Administrative Core: Dartmouth Medical SchoolU19AI091173 · NIAID · DARTMOUTH COLLEGE · PI SWARTS, STEVEN GREGORY · 2010 to 2014
$16.3M
NCI NIH HHS P30 CA023108NIAID NIH HHS U19 AI091173
6 · The paper itself

Abstract

Testing and verification are an integral part of any cycle to design, manufacture and improve a novel device intended for use in humans. In the case of testing Dartmouth's electron paramagnetic resonance (EPR) in vivo tooth dosimetry device, in vitro studies are needed throughout its development to test its performance, i.e. to verify its current capability for assessing dose in individuals potentially exposed to ionizing radiation. Since the EPR device uses the enamel of human teeth to assess dose, models that include human teeth have been an integral mechanism to carry out in vitro studies during development and testing its ability to meet performance standards for its ultimate intended in vivo use. As the instrument improves over time, new demands for in vitro studies change as well. This paper describes the tooth models used to perform in vitro studies and their evolution to meet the changing demands for testing in vivo EPR tooth dosimetry.

Indexed as

Models, BiologicalModels, ChemicalBiological AssayComputer SimulationElectron Spin Resonance SpectroscopyHumansRadiation DosageRadiometryReproducibility of ResultsSensitivity and SpecificityTooth

Identifiers

PMID27555657
PMCPMC5225979

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.