Evidence map›Paper›PMID 27555097›Full record

Trial reportThe American journal of medicine2017

Physical Activity in Obese Type 2 Diabetes After Gastric Bypass or Medical Management.

Jennifer Panosian, Su-Ann Ding, Marlene Wewalka, Donald C Simonson, Ann Goebel-Fabbri, Kathleen Foster, Florencia Halperin, Ashley Vernon, Allison B Goldfine

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in The American journal of medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01073020 (Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes), which is not on this map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01073020 nacompletednot on this map

Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes (SLIMM-T2D)

TypeinterventionalSponsorJoslin Diabetes CenterRan2010 to 2016Enrolled88ConditionsType 2 Diabetes Mellitus, ObesityArmsAllergan Adjustable Gastric Band Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group, Roux-en-Y Gastric Bypass (RYGB) Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Bypass Group
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Trial
  6. Trial
  7. Multidisciplinary Therapy to Target Obesity and Its Complications in Adult Population: A Narrative Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  8. Role of the exercise professional in metabolic and bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jennifer PanosianResearch Division, Section of Clinical Behavioral and Outcomes Research, Joslin Diabetes Center, Boston, Mass.
Su-Ann DingResearch Division, Section of Clinical Behavioral and Outcomes Research, Joslin Diabetes Center, Boston, Mass; Harvard Medical School, Boston, Mass.
Marlene WewalkaResearch Division, Section of Clinical Behavioral and Outcomes Research, Joslin Diabetes Center, Boston, Mass; Harvard Medical School, Boston, Mass.
Donald C SimonsonHarvard Medical School, Boston, Mass; Division of Endocrinology, Brigham and Women's Hospital, Boston, Mass.
Ann Goebel-FabbriResearch Division, Section of Clinical Behavioral and Outcomes Research, Joslin Diabetes Center, Boston, Mass; Harvard Medical School, Boston, Mass.
Kathleen FosterResearch Division, Section of Clinical Behavioral and Outcomes Research, Joslin Diabetes Center, Boston, Mass.
Florencia HalperinResearch Division, Section of Clinical Behavioral and Outcomes Research, Joslin Diabetes Center, Boston, Mass; Harvard Medical School, Boston, Mass; Division of Endocrinology, Brigham and Women's Hospital, Boston, Mass.
Ashley VernonHarvard Medical School, Boston, Mass; Division of Endocrinology, Brigham and Women's Hospital, Boston, Mass; Division of General & Gastrointestinal Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, Mass.
Allison B GoldfineResearch Division, Section of Clinical Behavioral and Outcomes Research, Joslin Diabetes Center, Boston, Mass; Harvard Medical School, Boston, Mass; Division of Endocrinology, Brigham and Women's Hospital, Boston, Mass. Electronic address: Allison.Goldfine@Joslin.Harvard.Edu.

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
Comparative Effectiveness of Medical Therapy vs. Bariatric Surgery for Obese T2DMRC1DK086918 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLDFINE, ALLISON B, LAUTZ, DAVID BRADLEY · 2009 to 2010
$1.0M
Durability and Mechanisms of Bariatric Surgery vs Medical Therapy in Obese T2DR56DK095451 · NIDDK · JOSLIN DIABETES CENTER · PI GOLDFINE, ALLISON B, LAUTZ, DAVID BRADLEY · 2012 to 2013
$277k
NIDDK NIH HHS P30 DK036836NIDDK NIH HHS R56 DK095451NIDDK NIH HHS RC1 DK086918
6 · The paper itself

Abstract

backgroundThe purpose of this study was to compare effects of Roux-en-Y gastric bypass versus a multidisciplinary, group-based medical diabetes and weight management program on physical fitness and behaviors.

methodsPhysical behavior and fitness were assessed in participants of the study Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes (SLIMM-T2D) (NCT01073020), a randomized, parallel-group trial conducted at a US academic hospital and diabetes clinic with 18- to 24-month follow-up. Thirty-eight type 2 diabetes patients with hemoglobin A

resultsBoth groups similarly improved 6-minute walk test distance, with greater improvements in oxygen saturation and reduced heart rate after surgery. Self-reported physical activity improved similarly at 18-24 months after interventions, although exercise increased gradually after surgery, whereas early substantial increases in the medical group were not fully sustained. Self-reported total and physical health were similar by Short Form-36 but improved more in the Impact of Weight on Quality of Life survey after surgery. Improvement in cardiovascular risk scores, HbA

conclusionIn this small, randomized study, both interventions led to therapeutic lifestyle changes and improved objective and self-reported physical fitness. Greater improvements in heart rate, oxygen saturation, and perceived impact of weight on health were seen after surgery, which could be attributable to greater weight loss. The clinical importance of these improvements with greater weight loss warrants further investigation.

Indexed as

ExerciseGastric BypassDiabetes Mellitus, Type 2FemaleHealth BehaviorHumansMaleMiddle AgedObesityPhysical FitnessWeight Reduction ProgramsBariatric surgeryObesityPhysical activityPhysical fitnessRoux-en-Y gastric bypassType 2 diabetes

Identifiers

PMID27555097
PMCPMC5164867

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.