ArticleThe Journal of allergy and clinical immunology2017
Exploiting CD22 on antigen-specific B cells to prevent allergy to the major peanut allergen Ara h 2.
Open access · greenAbstract readLetter
In one paragraph
Article in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 56 citations in OpenAlex.
- Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Molecular Insights into the Engagement of High-Affinity Sialylated Ligands to Human CD22.JACS Au · 2025Article
- Next-Generation Allergen-Specific Immunotherapy for Food Allergy.Clinical reviews in allergy & immunology · 2025Review
- Exploring Siglecs: Potential Modulators of Immune Cells in Food Allergy and Therapeutic Applications.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025Review
- Nanoparticle-Mediated Targeted Protein Degradation: An Emerging Therapeutics Technology.Angewandte Chemie (International ed. in English) · 2025Review
- Induced proximity at the cell surface.Nature biotechnology · 2025Review
- Mucins and Their Roles in Asthma.Immunological reviews · 2025Review
- Article
- Biomaterial engineering strategies for B cell immunity modulations.Biomaterials science · 2024Review
- Chemical immunology: Recent advances in tool development and applications.Cell chemical biology · 2024Review
- CD22L Conjugation to Insulin Attenuates Insulin-Specific B Cell Activation.Bioconjugate chemistry · 2023Article
- Siglecs as potential targets of therapy in human mast cell- and/or eosinophil-associated diseases.Seminars in immunology · 2023Review
- Glycomimetics for the inhibition and modulation of lectins.Chemical Society reviews · 2023Review
- Siglecs in allergy and asthma.Molecular aspects of medicine · 2023Review
- Impact of Siglecs on autoimmune diseases.Molecular aspects of medicine · 2023Review
- Targeting CD22 on memory B cells to induce tolerance to peanut allergens.The Journal of allergy and clinical immunology · 2022Article
- Suppressing Immune Responses Using Siglec Ligand-Decorated Anti-receptor Antibodies.Journal of the American Chemical Society · 2022Article
- Tolerogenic Nanoparticles Impacting B and T Lymphocyte Responses Delay Autoimmune Arthritis in K/BxN Mice.ACS chemical biology · 2021Article
- Emerging glyco-based strategies to steer immune responses.The FEBS journal · 2021Review
- Glycoengineering of NK Cells with Glycan Ligands of CD22 and Selectins for B-Cell Lymphoma Therapy.Angewandte Chemie (International ed. in English) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Kelly A OrgelDepartment of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC; UNC Food Allergy Initiative, Chapel Hill, NC; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC.
Shiteng DuanDepartment of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, Calif; Department of Chemical Physiology, The Scripps Research Institute, La Jolla, Calif; Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, Calif.
Benjamin L WrightDepartment of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC; UNC Food Allergy Initiative, Chapel Hill, NC; Department of Pediatrics, Duke University Medical Center, Durham, NC.
Soheila J MalekiUS Department of Agriculture, Agricultural Research Service, Southern Regional Research Center, New Orleans, La.
John C WolfUS Department of Agriculture, Agricultural Research Service, Southern Regional Research Center, New Orleans, La.
Brian P VickeryDepartment of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC; UNC Food Allergy Initiative, Chapel Hill, NC.
A Wesley BurksDepartment of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC; UNC Food Allergy Initiative, Chapel Hill, NC.
James C PaulsonDepartment of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, Calif; Department of Chemical Physiology, The Scripps Research Institute, La Jolla, Calif; Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, Calif.
Mike D KulisDepartment of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC; UNC Food Allergy Initiative, Chapel Hill, NC. Electronic address: mike.kulis@unc.edu.
Matthew S MacauleyDepartment of Chemical Physiology, The Scripps Research Institute, La Jolla, Calif.
University of North Carolina at Chapel Hill · USScripps Research Institute · USAgricultural Research Service · USDuke Medical Center · US
Funding
Viral and Host cDNA Libraries from 1918 Influenza CasesP01AI058113 · NIAID · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GARCIA-SASTRE, ADOLFO · 2004 to 2010
$20.3MREGULATION OF SIALOSIDE EXPRESSION IN LEUKOCYTESR01AI050143 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI PAULSON, JAMES C · 2003 to 2018
$7.0MRESEARCH TRAINING IN ALLERGY AND CLINICAL IMMUNOLOGYT32AI007062 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David B. Peden, John W. Sleasman · 1985 to 2026
$6.1MInducing antigen specific B cell toleranceR01AI099141 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI PAULSON, JAMES C · 2012 to 2016
$2.3MNIAID NIH HHS P01 AI058113NIAID NIH HHS R01 AI050143NIAID NIH HHS R01 AI099141NIAID NIH HHS T32 AI007062
Abstract
PubMed holds no abstract for this paper.
Indexed as
2S Albumins, PlantAnimalsAntigens, PlantB-LymphocytesDesensitization, ImmunologicFemaleGlycoproteinsLiposomesMiceMice, Inbred BALB CPeanut HypersensitivitySialic Acid Binding Ig-like Lectin 2Sialic Acid Binding Immunoglobulin-like LectinsTreatment Outcome2S Albumins, PlantAntigens, PlantAra h 2 allergen, Arachis hypogaeaCd22 protein, mouseGlycoproteinsLiposomesSialic Acid Binding Ig-like Lectin 2Sialic Acid Binding Immunoglobulin-like Lectins
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.