ArticleDiabetes2016
F1F0 ATP Synthase-Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline.
Article in Diabetes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 51 citations in OpenAlex.
- Encephalopathy: Cause, Pathogenesis, and Treatment.MedComm · 2026Review
- BAK and BAX: Therapeutic Targets for Acute Myocardial Infarction and Myocardial Ischemia-Reperfusion Injury.Biology · 2025Review
- FCGR2B knockdown alleviates diabetes-induced cognitive dysfunction by altering neuronal excitability.Molecular medicine (Cambridge, Mass.) · 2025Article
- Risk Factors, Pathological Changes, and Potential Treatment of Diabetes-Associated Cognitive Dysfunction.Journal of diabetes · 2025Review
- Mitochondrial CypD Acetylation Promotes Endothelial Dysfunction and Hypertension.Circulation research · 2024Article
- New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer's disease.Brain : a journal of neurology · 2024Article
- Caspase-3 cleaved tau impairs mitochondrial function through the opening of the mitochondrial permeability transition pore.Biochimica et biophysica acta. Molecular basis of disease · 2024Article
- Reactive Oxygen Species Damage Bovine Endometrial Epithelial Cells via the Cytochrome C-mPTP Pathway.Antioxidants (Basel, Switzerland) · 2023Article
- BMECs Ameliorate High Glucose-Induced Morphological Aberrations and Synaptic Dysfunction via VEGF-Mediated Modulation of Glucose Uptake in Cortical Neurons.Cellular and molecular neurobiology · 2023Article
- CryoEM Structure with ATP Synthase Enables Late-Stage Diversification of Cruentaren A.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023Article
- A Novel 5-Chloro-Molecules (Basel, Switzerland) · 2022Article
- Electrophysiological properties of the mitochondrial permeability transition pores: Channel diversity and disease implication.Biochimica et biophysica acta. Bioenergetics · 2021Review
- Hyperglycemia exacerbates ischemic stroke outcome independent of platelet glucose uptake.Journal of thrombosis and haemostasis : JTH · 2021Article
- A vaccine to prevent initial loss of cognition and eventual Alzheimer's disease in elderly persons.Alzheimer's & dementia (New York, N. Y.) · 2021Article
- Rhein Relieves Oxidative Stress in an AβFrontiers in pharmacology · 2021Article
- From Obesity to Hippocampal Neurodegeneration: Pathogenesis and Non-Pharmacological Interventions.International journal of molecular sciences · 2020Review
- Natural products and other inhibitors of FEuropean journal of medicinal chemistry · 2020Review
- Diabetes Mellitus, Mitochondrial Dysfunction and CaInternational journal of molecular sciences · 2020Review
- Deletion of the Mitochondrial Matrix Protein CyclophilinD Prevents Parvalbumin Interneuron Dysfunctionand Cognitive Deficits in a Mouse Model of NMDA Hypofunction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Mitochondrial ATP synthase regulates corpus cavernosum smooth muscle cell functionExperimental and therapeutic medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Mitochondrial abnormalities are well known to cause cognitive decline. However, the underlying molecular basis of mitochondria-associated neuronal and synaptic dysfunction in the diabetic brain remains unclear. Here, using a mitochondrial single-channel patch clamp and cyclophilin D (CypD)-deficient mice (Ppif
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.