Evidence map›Paper›PMID 27554184›Full record

Trial reportAppetite2016

Association between objective and subjective binge eating and psychopathology during a psychological treatment trial for bulimic symptoms.

Andrea B Goldschmidt, Erin C Accurso, Ross D Crosby, Li Cao, Jo Ellison, Tracey L Smith, Marjorie H Klein, James E Mitchell, Scott J Crow, Stephen A Wonderlich and 1 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Appetite, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  11. Reduced Inferior and Orbital Frontal Thickness in Adolescent Bulimia Nervosa Persists Over Two-Year Follow-Up.Journal of the American Academy of Child and Adolescent Psychiatry · 2017
    Article
  12. Are loss of control while eating and overeating valid constructs? A critical review of the literature.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2017
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Andrea B GoldschmidtDepartment of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, IL, USA. Electronic address: andrea.goldschmidta@lifespan.org.
Erin C AccursoDepartment of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Ross D CrosbyDepartment of Clinical Research, Neuropsychiatric Research Institute, Fargo, ND, USA; Department of Clinical Neuroscience, The University of North Dakota School of Medicine and Health Sciences, Fargo, ND, USA.
Li CaoDepartment of Clinical Research, Neuropsychiatric Research Institute, Fargo, ND, USA.
Jo EllisonDepartment of Clinical Research, Neuropsychiatric Research Institute, Fargo, ND, USA.
Tracey L SmithVA South Central Mental Illness Research, Education & Clinical Center, VA HSR&D Center for Innovations in Quality, Effectiveness & Safety (IQuEST), Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA.
Marjorie H KleinDepartment of Psychiatry, University of Wisconsin, Madison, WI, USA.
James E MitchellDepartment of Clinical Research, Neuropsychiatric Research Institute, Fargo, ND, USA; Department of Clinical Neuroscience, The University of North Dakota School of Medicine and Health Sciences, Fargo, ND, USA.
Scott J CrowDepartment of Psychiatry, University of Minnesota Medical School, Minneapolis, MN, USA; The Emily Program, St. Paul, MN, USA.
Stephen A WonderlichDepartment of Clinical Research, Neuropsychiatric Research Institute, Fargo, ND, USA; Department of Clinical Neuroscience, The University of North Dakota School of Medicine and Health Sciences, Fargo, ND, USA.
Carol B PetersonDepartment of Psychiatry, University of Minnesota Medical School, Minneapolis, MN, USA.
Neuropsychiatric Research Institute · USUniversity of Minnesota Medical Center · USBaylor College of Medicine · USUniversity of California, San Francisco · USUniversity of Chicago · USUniversity of North Dakota · USUniversity of Wisconsin–Madison · US

Funding

Obesity and Energy Metabolism CoreP30DK050456 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI CROW, SCOTT J · 1995 to 2015
$17.0M
Regional Postdoctoral Training Grant in Eating Disorders ResearchT32MH082761 · NIMH · UNIVERSITY OF MINNESOTA · PI CAROL B. PETERSON · 2009 to 2026
$6.2M
Ecological Momentary Assessment of Anorexia NervosaR01MH059674 · NIMH · SANFORD RESEARCH NORTH · PI WONDERLICH, STEPHEN ARTHUR · 2000 to 2009
$2.1M
The Treatment of Binge Eating DisorderR01DK061912 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI CROW, SCOTT J · 2002 to 2004
$868k
Development of 13C-retinol isotope dilution techniquesR01DK061973 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI TANUMIHARDJO, SHERRY A · 2002 to 2006
$727k
THE TREATMENT OF EATING DISORDERSK02MH065919 · NIMH · UNIVERSITY OF MINNESOTA TWIN CITIES · PI CROW, SCOTT J · 2003 to 2007
$689k
Neurodevelopmental substrates of emotion regulation in obese, binge eating youthK23DK105234 · NIDDK · UNIVERSITY OF CHICAGO · PI GOLDSCHMIDT, ANDREA BETH · 2015 to 2018
$673k
Integrative Cognitive-Affective Therapy for Bulimia NervosaR34MH077571 · NIMH · SANFORD RESEARCH NORTH · PI WONDERLICH, STEPHEN ARTHUR · 2007 to 2009
$590k
NIDDK NIH HHS K23 DK105234NIDDK NIH HHS P30 DK050456NIDDK NIH HHS R01 DK061912NIDDK NIH HHS R01 DK061973NIMH NIH HHS K02 MH065919NIMH NIH HHS R01 MH059674NIMH NIH HHS R34 MH077571NIMH NIH HHS T32 MH082761
6 · The paper itself

Abstract

Although loss of control (LOC) while eating is a core construct of bulimia nervosa (BN), questions remain regarding its validity and prognostic significance independent of overeating. We examined trajectories of objective and subjective binge eating (OBE and SBE, respectively; i.e., LOC eating episodes involving an objectively or subjectively large amount of food) among adults participating in psychological treatments for BN-spectrum disorders (n = 80). We also explored whether changes in the frequency of these eating episodes differentially predicted changes in eating-related and general psychopathology and, conversely, whether changes in eating-related and general psychopathology predicted differential changes in the frequency of these eating episodes. Linear mixed models with repeated measures revealed that OBE decreased twice as rapidly as SBE throughout treatment and 4-month follow-up. Generalized linear models revealed that baseline to end-of-treatment reductions in SBE frequency predicted baseline to 4-month follow-up changes in eating-related psychopathology, depression, and anxiety, while changes in OBE frequency were not predictive of psychopathology at 4-month follow-up. Zero-inflation models indicated that baseline to end-of-treatment changes in eating-related psychopathology and depression symptoms predicted baseline to 4-month follow-up changes in OBE frequency, while changes in anxiety and self-esteem did not. Baseline to end-of-treatment changes in eating-related psychopathology, self-esteem, and anxiety predicted baseline to 4-month follow-up changes in SBE frequency, while baseline to end-of-treatment changes in depression did not. Based on these findings, LOC accompanied by objective overeating may reflect distress at having consumed an objectively large amount of food, whereas LOC accompanied by subjective overeating may reflect more generalized distress related to one's eating- and mood-related psychopathology. BN treatments should comprehensively target LOC eating and related psychopathology, particularly in the context of subjectively large episodes, to improve global outcomes.

Indexed as

AdultAnxietyBulimiaBulimia NervosaCognitive Behavioral TherapyDepressionFemaleHumansHyperphagiaMalePsychopathologySelf ConceptStress, PsychologicalBinge eatingBulimia nervosaLoss of control eatingPsychopathologyValidity

Identifiers

PMID27554184
PMCPMC5457535
OpenAlexW2513230519

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.