Evidence map›Paper›PMID 27553984›Full record

ArticlePharmacological research2016

S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics.

Katalin Módis, YoungJun Ju, Akbar Ahmad, Ashley A Untereiner, Zaid Altaany, Lingyun Wu, Csaba Szabo, Rui Wang

Open access · greenAbstract read
In one paragraph

Article in Pharmacological research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 1 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 1 synthesis or guideline pooled it, 195 citations in OpenAlex.

  1. Pooled it
  2. HPlant cell reports · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Hydrogen Sulfide Signaling in Neurodegenerative Movement Disorders.Handbook of experimental pharmacology · 2026
    Review
  7. HFrontiers in cell and developmental biology · 2026
    Review
  8. Review
  9. Review
  10. Article
  11. Antioxidants (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Persulfidation of Human CystathionineAntioxidants (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Hydrogen sulfide and its role in female reproduction.Frontiers in veterinary science · 2024
    Review
  16. Regulation of Mitochondrial Respiration by Hydrogen Sulfide.Antioxidants (Basel, Switzerland) · 2023
    Review
  17. Review
  18. Article
  19. Advances of HAntioxidants (Basel, Switzerland) · 2023
    Review
  20. HAntioxidants (Basel, Switzerland) · 2023
    Review

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Katalin MódisCardiovascular and Metabolic Research Unit, Lakehead University, Thunder Bay, ON, Canada; Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA; Department of Anesthesiology, University of Texas Medical Branch, Galveston, TX, USA.
YoungJun JuCardiovascular and Metabolic Research Unit, Lakehead University, Thunder Bay, ON, Canada.
Akbar AhmadDepartment of Anesthesiology, University of Texas Medical Branch, Galveston, TX, USA.
Ashley A UntereinerCardiovascular and Metabolic Research Unit, Lakehead University, Thunder Bay, ON, Canada; Department of Anesthesiology, University of Texas Medical Branch, Galveston, TX, USA.
Zaid AltaanyCardiovascular and Metabolic Research Unit, Lakehead University, Thunder Bay, ON, Canada.
Lingyun WuSchool of Human Kinesiology, Laurentian University, Sudbury, ON, Canada.
Csaba SzaboDepartment of Anesthesiology, University of Texas Medical Branch, Galveston, TX, USA. Electronic address: szabocsaba@aol.com.
Rui WangCardiovascular and Metabolic Research Unit, Lakehead University, Thunder Bay, ON, Canada; Department of Biology, Laurentian University, ON, Canada. Electronic address: rui.wang@laurentian.ca.
The University of Texas Medical Branch at Galveston · USLakehead University · CALaurentian University · CA

Funding

Regulation of cellular bioenergetics by hydrogen sulfideR01GM107846 · NIGMS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SZABO, CSABA · 2014 to 2017
$1.2M
CIHRNIGMS NIH HHS R01 GM107846
6 · The paper itself

Abstract

Mammalian cells can utilize hydrogen sulfide (H

Indexed as

Adenosine TriphosphateAnimalsCell LineCell Line, TumorCystathionine gamma-LyaseCysteineEnergy MetabolismHEK293 CellsHep G2 CellsHumansHydrogen SulfideLiverMaleMiceMitochondriaMitochondrial Proton-Translocating ATPasesAdenosine TriphosphateCystathionine gamma-LyaseCysteineHydrogen SulfideMitochondrial Proton-Translocating ATPasesATP synthaseBioenergeticsBurnBurn injuryCysteineH(2)SHydrogen sulfideMitochondriaS-Sulfhydration

Identifiers

PMID27553984
PMCPMC5107138
OpenAlexW2514610147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.