Evidence map›Paper›PMID 27553932›Full record

ArticleEuropean radiology2017

Gastric cancer: texture analysis from multidetector computed tomography as a potential preoperative prognostic biomarker.

Francesco Giganti, Sofia Antunes, Annalaura Salerno, Alessandro Ambrosi, Paolo Marra, Roberto Nicoletti, Elena Orsenigo, Damiano Chiari, Luca Albarello, Carlo Staudacher and 3 more

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Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it, 110 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. A radiomics nomogram for the prediction of overall survival in patients with hepatocellular carcinoma after hepatectomy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2020
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  16. Predictive value ofJournal of cancer research and clinical oncology · 2023
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  17. Review
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Francesco GigantiDepartment of Radiology and Centre for Experimental Imaging San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy. giganti.fra@gmail.com.
Sofia AntunesCentre for Experimental Imaging, San Raffaele Scientific Institute, Milan, Italy.
Annalaura SalernoDepartment of Radiology and Centre for Experimental Imaging San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Alessandro AmbrosiSan Raffaele Vita-Salute University, Milan, Italy.
Paolo MarraDepartment of Radiology and Centre for Experimental Imaging San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Roberto NicolettiDepartment of Radiology and Centre for Experimental Imaging San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Elena OrsenigoDepartment of Surgery, San Raffaele Scientific Institute, Milan, Italy.
Damiano ChiariSan Raffaele Vita-Salute University, Milan, Italy.
Luca AlbarelloPathology Unit, San Raffaele Scientific Institute, Milan, Italy.
Carlo StaudacherSan Raffaele Vita-Salute University, Milan, Italy.
Antonio EspositoDepartment of Radiology and Centre for Experimental Imaging San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Alessandro Del MaschioDepartment of Radiology and Centre for Experimental Imaging San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Francesco De CobelliDepartment of Radiology and Centre for Experimental Imaging San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
San Raffaele University of Rome · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the association between preoperative texture analysis from multidetector computed tomography (MDCT) and overall survival in patients with gastric cancer.

methodsInstitutional review board approval and informed consent were obtained. Fifty-six patients with biopsy-proved gastric cancer were examined by MDCT and treated with surgery. Image features from texture analysis were quantified, with and without filters for fine to coarse textures. The association with survival time was assessed using Kaplan-Meier and Cox analysis.

resultsThe following parameters were significantly associated with a negative prognosis, according to different thresholds: energy [no filter] - Logarithm of relative risk (Log RR): 3.25; p = 0.046; entropy [no filter] (Log RR: 5.96; p = 0.002); entropy [filter 1.5] (Log RR: 3.54; p = 0.027); maximum Hounsfield unit value [filter 1.5] (Log RR: 3.44; p = 0.027); skewness [filter 2] (Log RR: 5.83; p = 0.004); root mean square [filter 1] (Log RR: - 2.66; p = 0.024) and mean absolute deviation [filter 2] (Log RR: - 4.22; p = 0.007).

conclusionsTexture analysis could increase the performance of a multivariate prognostic model for risk stratification in gastric cancer. Further evaluations are warranted to clarify the clinical role of texture analysis from MDCT. KEY POINTS: • Textural analysis from computed tomography can be applied in gastric cancer. • Preoperative non-invasive texture features are related to prognosis in gastric cancer. • Texture analysis could help to evaluate the aggressiveness of this tumour.

Indexed as

AdenocarcinomaAgedBiomarkersBiopsyCarcinoma, Signet Ring CellFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultidetector Computed TomographyMultivariate AnalysisNeoplasm StagingPrognosisProportional Hazards ModelsRetrospective StudiesBiomarkersGastric cancerMedical oncologyMultidetector computed tomographyPrognosisSurvival

Identifiers

PMID27553932
OpenAlexW2517804208

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.