ArticleEuropean radiology2017
The porta hepatis microcyst: an additional sonographic sign for the diagnosis of biliary atresia.
Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- The diagnostic performance of ultrasound features for biliary atresia: a systematic review and updated meta-analysis.Pediatric surgery international · 2025Pooled it
- Comparison for the diagnostic performance of early diagnostic methods for biliary atresia: a systematic review and network meta-analysis.Pediatric surgery international · 2024Pooled it
- Practical approach to imaging diagnosis of biliary atresia, Part 1: prenatal ultrasound and magnetic resonance imaging, and postnatal ultrasound.Pediatric radiology · 2021Pooled it
- Diagnostic dilemma of cystic biliary atresia: A series of two cases and brief review of the diagnostic modalities.JPGN reports · 2026Article
- Key postnatal magnetic resonance characteristics for differentiating cystic biliary atresia from choledochal cyst.European radiology · 2024Article
- Diagnostic Accuracy of Ultrasound in Cholestatic Infants with Biliary Atresia.Turkish archives of pediatrics · 2024Article
- [Developmental disorders of the gastrointestinal tract].Radiologie (Heidelberg, Germany) · 2024Article
- Diseases of bile duct in children.World journal of gastroenterology · 2024Review
- Preoperative imaging findings to predict 2-year native liver survival after the Kasai procedure in patients with biliary atresia.European radiology · 2024Article
- Interpretable artificial intelligence-based app assists inexperienced radiologists in diagnosing biliary atresia from sonographic gallbladder images.BMC medicine · 2024Article
- Development and validation of a model for early diagnosis of biliary atresia.BMC pediatrics · 2023Observational
- Anomalies of the fetal gallbladder: pre-and postnatal correlations.Pediatric radiology · 2023Article
- Percutaneous ultrasound-guided cholecystocholangiography with microbubbles combined with liver biopsy for the assessment of suspected biliary atresia.Pediatric radiology · 2022Article
- Neonatal diagnosis of biliary atresia: a practical review and update.Pediatric radiology · 2022Review
- Ultrasound for the Diagnosis of Biliary Atresia: From Conventional Ultrasound to Artificial Intelligence.Diagnostics (Basel, Switzerland) · 2021Review
- Ultrasound characteristics combined with gamma-glutamyl transpeptidase for diagnosis of biliary atresia in infants less than 30 days.Pediatric surgery international · 2021Article
- The Prognosis of Type III Biliary Atresia with Hilar Cyst.Indian journal of pediatrics · 2021Article
- Key imaging features for differentiating cystic biliary atresia from choledochal cyst: prenatal ultrasonography and postnatal ultrasonography and MRI.Ultrasonography (Seoul, Korea) · 2021Article
- Three-color risk stratification for improving the diagnostic accuracy for biliary atresia.European radiology · 2020Article
- Neonatal Jaundice.Indian journal of pediatrics · 2019Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo describe and evaluate an additional sonographic sign in the diagnosis of biliary atresia (BA), the microcyst of the porta hepatis, in comparison with previously described signs.
methodsUltrasound performed in 321 infants (mean age 55 days) with cholestasis were retrospectively analyzed. BA was surgically confirmed in 193 patients and excluded in 128. US evaluated gallbladder type (1: normal; 2: consistent with BA; 3: suspicious), triangular cord sign (TCS), microcyst and macrocyst, polysplenia syndrome, portal hypertension, and bile duct dilatation. T test and Pearson χ
resultsThe highest specificity and sensitivity for BA (p < 0.001) were respectively obtained with non-visible gallbladder (100 %-13 %), macrocyst (99 %-10 %), polysplenia (99 %-11 %), microcyst (98 %-20 %), type 2 gallbladder (98 %-34 %), and TCS (97 %-30 %). Combination of signs (macro or microcyst; cyst and no bile duct dilatation; microcyst and/or TCS; type 2 gallbladder and/or cyst) provided better sensitivities (25-49 %) with similar specificities (95-98 %) (p < 0.001). On univariate analysis, the single US signs most strongly associated with BA were polysplenia (odds ratio, OR 16.3), macrocyst (OR 14.7), TCS (OR 13.4) and microcyst (OR 8).
conclusionsPorta hepatis microcyst is a reliable US sign for BA diagnosis. KEY POINTS: • The porta hepatis microcyst is a specific sign of biliary atresia. • It was found in 31 (16.1 %) of 193 patients with biliary atresia. • Its specificity was 98 % (p < 0.001). • High frequency transducer and color Doppler can show the porta hepatis microcyst.
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